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Alnylam Pharmaceuticals

247.51

-10.4900-4.07%

Post-market: 247.00-0.5100-0.21%16:44 EDT

Volume:1.55M

Turnover:384.60M

Market Cap:33.02B

PE:44.05

High:256.68

Open:256.68

Low:246.42

Close:258.00

52wk High:495.55

52wk Low:197.81

Shares:133.43M

Float Shares:133.16M

Volume Ratio:0.78

T/O Rate:1.16%

Dividend:- -

Dividend Rate:- -

EPS(TTM):5.62

EPS(LYR):2.33

ROE:96.55%

ROA:12.34%

PB:24.39

PE(LYR):106.23

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Overview Company News Filings

Press Release: Alnylam to Webcast Conference Call Discussing Second Quarter 2026 Financial Results

Alnylam Schedules Conference Call on Second-quarter 2026 Results

Alnylam Initiates Phase 2 Trial of Mivelsiran in Down Syndrome-associated Alzheimer’s Disease

Alnylam Pharmaceuticals' Q2 Results to Determine 2026 Revenue Outlook, BofA Securities Says

MT Newswires Live

Analysts Have Conflicting Sentiments on These Healthcare Companies: Alnylam Pharma (ALNY), Madrigal Pharmaceuticals (MDGL) and Krystal Biotech (KRYS)

BofA Securities Cuts Alnylam Pharmaceuticals Price Target to $410 From $460, Maintains Buy Rating

MT Newswires Live

Alnylam Pharmaceuticals is Maintained at Buy by HC Wainwright & Co.

Analysts Offer Insights on Healthcare Companies: Immuneering (IMRX), Vera Therapeutics (VERA) and Alnylam Pharma (ALNY)

Movement Alert｜Alnylam Pharmaceuticals Falls 5.29% in Regular Trading, Trading at $281.53

Alnylam price target lowered to $410 from $505 at Truist

Alnylam Pharmaceuticals Inc : Truist Securities Cuts Target Price to $410 from $505

THOMSON REUTERS

NASDAQ Top and Bottom Performing Stocks at About 02:45 P.m. EDT on 2026-07-10

Movement Alert｜Alnylam Pharmaceuticals Falls 5.08% in Regular Trading, Trading at $296.89

Alnylam Pharmaceuticals is Maintained at Equal-weight by Morgan Stanley

Alnylam Pharmaceuticals (ALNY) Could Be 28% Undervalued Following Rival ATTR Trial Failure

Simply Wall St.

Analysts Offer Insights on Healthcare Companies: Simulations Plus (SLP), Alnylam Pharma (ALNY) and Revolution Medicines (RVMD)

Alnylam, Bridgebio Gain from Astrazeneca-ionis Drug Missing Target

Raymond James Adjusts Price Target on Alnylam Pharmaceuticals to $468 From $420, Maintains Outperform Rating

MT Newswires Live

AstraZeneca PLC Stock (AZN) Moved Down by 6.72% on Jul 9: A Full Analysis

NASDAQ Top and Bottom Performing Stocks at About 11:01 A.m. EDT on 2026-07-09

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(Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that it will report financial results for the sec","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PBE","LU0882574055.USD","BK4139","ALNY","BK4588","BK4548","BK4585","LU0114720955.EUR","LU0889565916.HKD","LU0109394709.USD","LU0320765992.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2651441541","title":"Alnylam Schedules Conference Call on Second-quarter 2026 Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2651441541","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2651441541?lang=en_us&edition=fundamental","pubTime":"2026-07-16 20:00","pubTimestamp":1784203216,"startTime":"0","endTime":"0","summary":"Alnylam schedules conference call on second-quarter 2026 resultsAlnylam schedules second-quarter results release for July 30, 2026, before the US market open.Management to host an earnings conference ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260716:nNDL3ZSSJC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4548","BK4588","LU0114720955.EUR","PBE","BK4139","LU0109394709.USD","LU0889565916.HKD","BK4585","LU0320765992.SGD","ALNY","LU0882574055.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2651430205","title":"Alnylam Initiates Phase 2 Trial of Mivelsiran in Down Syndrome-associated Alzheimer’s Disease","url":"https://stock-news.laohu8.com/highlight/detail?id=2651430205","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2651430205?lang=en_us&edition=fundamental","pubTime":"2026-07-15 15:30","pubTimestamp":1784100618,"startTime":"0","endTime":"0","summary":"Alnylam initiates Phase 2 trial of mivelsiran in Down syndrome-associated Alzheimer’s diseaseAlnylam initiated a Phase 2 trial of mivelsiran in Down syndrome-associated early-stage Alzheimer’s disease, expanding its clinical Alzheimer’s program.Enrollment completed in the Phase 2 cAPPricorn-1 study of mivelsiran in cerebral amyloid angiopathy; initial results expected in 2028.Phase 1 mivelsiran data in early-onset Alzheimer’s showed no increased ARIA signal; mean maximum CSF reductions reached 89.9% for sAPPβ.Disclaimer:This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Alnylam Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire  on July 15, 2026, and is solely responsible for the information contain","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260715:nNDL797Ymk:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0109394709.USD","ALNY","BK4588","LU0320765992.SGD","BK4139","LU0114720955.EUR","LU0882574055.USD","PBE","BK4548","BK4585","LU0889565916.HKD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2651102563","title":"Alnylam Pharmaceuticals' Q2 Results to Determine 2026 Revenue Outlook, BofA Securities 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to stabilizers, according to the note.Analysts said they now expect longer Amvuttra net price erosion through 2031 as competitive and payor dynamics continue to impact price, and estimate potential peak sales in ATTR-CM across Amvuttra and nucresiran of $11.8 billion, down from $14.6 billion previously.BofA Securities kept its ","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["ALNY"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2651105476","title":"Analysts Have Conflicting Sentiments on These Healthcare Companies: Alnylam Pharma (ALNY), Madrigal Pharmaceuticals (MDGL) and Krystal 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NewswiresJuly 13, 2026 11:57 ET","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ALNY"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2651100961","title":"Analysts Offer Insights on Healthcare Companies: Immuneering (IMRX), Vera Therapeutics (VERA) and Alnylam Pharma (ALNY)","url":"https://stock-news.laohu8.com/highlight/detail?id=2651100961","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2651100961?lang=en_us&edition=fundamental","pubTime":"2026-07-13 23:00","pubTimestamp":1783954842,"startTime":"0","endTime":"0","summary":"Companies in the 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Alert｜Alnylam Pharmaceuticals Falls 5.08% in Regular Trading, Trading at $296.89","url":"https://stock-news.laohu8.com/highlight/detail?id=1184780518","media":"Market Focus","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1184780518?lang=en_us&edition=fundamental","pubTime":"2026-07-11 00:52","pubTimestamp":1783702377,"startTime":"0","endTime":"0","summary":"On July 11, Alnylam Pharmaceuticals fell 5.08% in regular trading, trading at $296.89 USD/share, with Turnover of $334 million.Within the Biotechnology sector where Alnylam Pharmaceuticals belongs,...","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ALNY"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650113347","title":"Alnylam Pharmaceuticals is Maintained at Equal-weight by Morgan Stanley","url":"https://stock-news.laohu8.com/highlight/detail?id=2650113347","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650113347?lang=en_us&edition=fundamental","pubTime":"2026-07-10 21:56","pubTimestamp":1783691760,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/ALNY/analyst-ratings(END) Dow Jones NewswiresJuly 10, 2026 09:56 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20:29","pubTimestamp":1783686596,"startTime":"0","endTime":"0","summary":"Why Alnylam Pharmaceuticals Stock Is Back in Focus\nAlnylam Pharmaceuticals (ALNY) moved sharply higher after a late stage trial for a competing transthyretin amyloid cardiomyopathy treatment from AstraZeneca and Ionis Pharmaceuticals failed, shifting investor attention toward Alnylam’s ATTR portfolio.\nSee our latest analysis for Alnylam Pharmaceuticals.\nThat ATTR news lands on top of a mixed year for Alnylam Pharmaceuticals, with the share price at $312.79, a year to date share price decline...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-alny/alnylam-pharmaceuticals/news/alnylam-pharmaceuticals-alny-could-be-28-undervalued-followi","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-alny/alnylam-pharmaceuticals/news/alnylam-pharmaceuticals-alny-could-be-28-undervalued-followi","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["PBE","BK4588","LU0882574055.USD","LU0320765992.SGD","ATTR","LU0114720955.EUR","LU0109394709.USD","ALNY","BK4548","LU0889565916.HKD","BK4139","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650871071","title":"Analysts Offer Insights on Healthcare Companies: Simulations Plus (SLP), Alnylam Pharma (ALNY) and Revolution Medicines (RVMD)","url":"https://stock-news.laohu8.com/highlight/detail?id=2650871071","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650871071?lang=en_us&edition=fundamental","pubTime":"2026-07-10 20:01","pubTimestamp":1783684888,"startTime":"0","endTime":"0","summary":"Analysts have been eager to weigh in on the Healthcare sector with new ratings on Simulations Plus (SLP), Alnylam Pharma (ALNY) and Revolution 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Bridgebio Gain from Astrazeneca-ionis Drug Missing Target","url":"https://stock-news.laohu8.com/highlight/detail?id=2650497560","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650497560?lang=en_us&edition=fundamental","pubTime":"2026-07-10 00:21","pubTimestamp":1783614060,"startTime":"0","endTime":"0","summary":"1222 ET - The failure of Wainua, a heart disease drug developed by AstraZeneca and Ionis, to meet a primary endpoint in a phase 3 trial is a positive for both BridgeBio Pharma and Alnylam Pharmaceuticals, according to Jefferies analysts. For BridgeBio, the news is a potential clearing event for its Attruby drug, an oral stabilizer that addresses the same rare heart disease known as transthyretin amyloid cardiomyopathy. It's also a headwind for Alnylam, whose Amvuttra treatment will remain the only gene silencer for ATTR-CM, the analysts write, although long-term questions remain for the company's next-generation silencer. Alnylam stock is up 2.4%, erasing some gains after opening up 16%. BridgeBio shares gain 15%.  Dow Jones NewswiresJuly 09, 2026 12:21 ET Copyright  2026 Dow Jones & Company, Inc.","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AZNH","LU0889565916.HKD","LU1267930573.SGD","LU2237443622.USD","LU2456880835.USD","LU0708994859.HKD","LU0109394709.USD","LU0029864427.USD","LU1829250122.USD","LU2089984988.USD","BK4588","BK4585","PBE","BK4568","LU0882574055.USD","LU0310800379.SGD","LU0114720955.EUR","BK4139","LU0432979614.USD","LU0289739699.SGD","LU0128525929.USD","BK4007","LU2237443895.HKD","BK4548","LU2237443382.USD","LU2468319806.SGD","LU2237443549.SGD","LU2237443465.HKD","LU2237443978.SGD","LU2462157665.USD","ALNY","LU2236285917.USD","LU0320765992.SGD","BBIO","AZN","BK4505","IE00B3T34201.USD","LU0058720904.USD","IONS","LU2417539215.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650973274","title":"Raymond James Adjusts Price Target on Alnylam Pharmaceuticals to $468 From $420, Maintains Outperform Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2650973274","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650973274?lang=en_us&edition=fundamental","pubTime":"2026-07-09 23:45","pubTimestamp":1783611901,"startTime":"0","endTime":"0","summary":"Alnylam Pharmaceuticals (ALNY) has an average rating of overweight and mean price target of $444.35, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic researc","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["RJF","ALNY"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650973322","title":"AstraZeneca PLC Stock (AZN) Moved Down by 6.72% on Jul 9: A Full Analysis","url":"https://stock-news.laohu8.com/highlight/detail?id=2650973322","media":"TradingKey","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650973322?lang=en_us&edition=fundamental","pubTime":"2026-07-09 23:15","pubTimestamp":1783610111,"startTime":"0","endTime":"0","summary":"• AstraZeneca shares fell after the Wainua drug failed a late-stage clinical trial.\n• The CARDIO-TTRansform trial did not meet its primary cardiovascular mortality reduction objectives.\n• High usage of competitor medication likely masked the drug's therapeutic efficacy in patients.","market":"hk","thumbnail":"https://resource.tradingkey.com/uploads/20251024/AstraZeneca-000ba9f6d3d446b080935cd9fe1dade4.jpg","type":0,"news_type":0,"thumbnails":["https://resource.tradingkey.com/uploads/20251024/AstraZeneca-000ba9f6d3d446b080935cd9fe1dade4.jpg"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tradingkey.com/news/market-movers/262020541-market-movers-azn-20260709","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0029864427.USD","BK4007","LU2237443895.HKD","PBE","LU2237443382.USD","LU0128525929.USD","LU2237443978.SGD","IE00B3T34201.USD","LU0114720955.EUR","LU0310800379.SGD","LU0432979614.USD","LU2089984988.USD","BK4568","LU0058720904.USD","LU2237443622.USD","LU2417539215.USD","LU2456880835.USD","LU2237443465.HKD","LU0882574055.USD","LU2237443549.SGD","ALNY","BK4588","IONS","LU2462157665.USD","LU2236285917.USD","LU0889565916.HKD","LU2468319806.SGD","LU0109394709.USD","BK4548","BK4585","AZN","LU0708994859.HKD","LU1829250122.USD","BK4139","LU1267930573.SGD","LU0320765992.SGD","BBIO","AZNH","LU0289739699.SGD","BK4505"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650978280","title":"NASDAQ Top and Bottom Performing Stocks at About 11:01 A.m. 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