US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

Karyopharm Therapeutics

1.61

-0.0100-0.62%

Post-market: 1.60-0.0096-0.60%17:48 EDT

Volume:6.74M

Turnover:9.67M

Market Cap:36.49M

PE:-0.12

High:1.61

Open:1.50

Low:1.24

Close:1.62

52wk High:10.99

52wk Low:1.24

Shares:22.66M

Float Shares:15.77M

Volume Ratio:8.46

T/O Rate:42.70%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-13.0816

EPS(LYR):-17.9300

ROE:-891.05%

ROA:-47.61%

PB:-0.11

PE(LYR):-0.09

Loading ...

Overview Company News Filings

Major Issues Report

8-K - Current report

Major Issues Report

8-K - Current report

Quarterly Report

10-Q - Quarterly report [Sections 13 or 15(d)]

Major Issues Report

8-K - Current report

Major Issues Report

8-K - Current report

Employee Stock Ownership

S-8 - Securities to be offered to employees in employee benefit plans

Annual Report

10-K - Annual report [Section 13 and 15(d), not S-K Item 405]

Beneficial Ownership Change

SC 13G/A [Amend] - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13G/A [Amend] - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13G/A [Amend] - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13G/A [Amend] - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13G/A [Amend] - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13G/A [Amend] - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13G - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13G/A [Amend] - Statement of acquisition of beneficial ownership by individuals

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13G/A [Amend] - Statement of acquisition of beneficial ownership by individuals

Major Issues Report

8-K - Current report

Major Issues Report

8-K - Current report

Major Issues Report

8-K - Current report

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Tiger Brokers HK | Online Trading in stocks, bonds & ETFS","description":"Discover Tiger Brokers HK, an online trading platform for stocks&ETFs, options&futures, bonds and crypto. Open an account to enjoy low commission trading today!","keywords":"tiger trading,tiger security,tiger broker hk,tigers co ltd,tiger trade hk,tiger brokers hk,stock broker,securities broker,online brokerage,hong kong broker,hk broker,online stock trading,online trading platform,stock trading platforms,trading application,stock trading,stock trading hong kong,buying stocks in hong kong,tiger brokers","social":{"ogDescription":"Discover Tiger Brokers HK, an online trading platform for stocks&ETFs, options&futures, bonds and crypto. Open an account to enjoy low commission trading today!","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://www.atigreclipse.com/stock/KPTI/filings?page=8"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"HKG","license":"TBHK","edition":"fundamental","symbol":"KPTI","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"KPTI\",,,,,undefined,":{"symbol":"KPTI","market":"US","secType":"STK","nameCN":"Karyopharm Therapeutics","latestPrice":1.61,"timestamp":1789156800000,"preClose":1.62,"halted":0,"volume":6735085,"hourTrading":{"tag":"盘后","latestPrice":1.6004,"preClose":1.61,"latestTime":"17:48 EDT","volume":11111,"amount":17858.521413,"timestamp":1789163331749,"change":-0.0096,"changeRate":-0.005963,"amplitude":0.018634},"delay":0,"changeRate":-0.006172839506172844,"floatShares":15774200,"shares":22662943,"eps":-13.0816,"marketStatus":"Post-Mkt","change":-0.01,"latestTime":"09-11 18:03:38 EDT","open":1.5,"high":1.61,"low":1.24,"amount":9666722.022664001,"amplitude":0.228395,"askPrice":1.65,"askSize":923,"bidPrice":1.47,"bidSize":100,"shortable":0,"etf":0,"ttmEps":-13.0816,"tradingStatus":3,"nextMarketStatus":{"tag":"Closed","tradingStatus":0,"beginTime":1789171200000},"marketStatusCode":4,"adr":0,"adrRate":0,"listingDate":1383714000000,"exchange":"NASDAQ","adjPreClose":1.62,"preHourTrading":{"tag":"盘前","latestPrice":1.51,"preClose":1.62,"latestTime":"09:29 EDT","volume":444740,"amount":627966.43127,"timestamp":1789133399999,"change":-0.11,"changeRate":-0.067901,"amplitude":0.271605},"postHourTrading":{"tag":"盘后","latestPrice":1.6004,"preClose":1.61,"latestTime":"17:48 EDT","volume":11111,"amount":17858.521413,"timestamp":1789163331749,"change":-0.0096,"changeRate":-0.005963,"amplitude":0.018634},"volumeRatio":8.46478,"impliedVol":1.3158,"impliedVolPercentile":0.3785},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"KPTI\",,,,,undefined,":{"symbol":"KPTI","floatShares":15774200,"roa":"-47.61%","roe":"-891.05%","lyrEps":-17.93,"volumeRatio":8.46478,"shares":22662943,"dividePrice":0,"high":1.61,"amplitude":0.228395,"preClose":1.62,"low":1.24,"week52Low":1.24,"pbRate":"-0.11","psRate":"0.25","week52High":10.99,"institutionHeld":0,"latestPrice":1.61,"committee":-0.804497,"eps":-13.0816,"divideRate":0,"volume":6735085,"delay":0,"ttmEps":-13.0816,"open":1.5,"prevYearClose":7.36,"prevWeekClose":1.79,"prevMonthClose":2.06,"prevQuarterClose":9.77,"fiveDayClose":1.77,"twentyDayClose":1.99,"sixtyDayClose":9.1},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/KPTI\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-08-13","symbol":"KPTI","fiscalQuarterEnding":"2026/06","expectedEps":-1.53,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1786593600000,"reportTimeType":"pre","actualEps":-2.32},{"market":"US","date":"2026-05-14","symbol":"KPTI","fiscalQuarterEnding":"2026/03","expectedEps":-1.45,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1778731200000,"reportTimeType":"pre","actualEps":-1.24},{"market":"US","date":"2026-02-12","symbol":"KPTI","fiscalQuarterEnding":"2025/12","expectedEps":-2.26,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1770872400000,"reportTimeType":"pre","actualEps":-3.6},{"date":"2026-01-12","symbol":"KPTI","type":"earning","reportTimeType":"pre","market":"US","fiscalQuarterEnding":null,"expectedEps":null,"defaultRemindTime":1768208400000,"name":null,"time":"Pre-MKt","dateTimestamp":1768194000000,"actualEps":null},{"market":"US","date":"2025-11-03","symbol":"KPTI","fiscalQuarterEnding":"2025/09","expectedEps":-3.3,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1762146000000,"reportTimeType":"pre","actualEps":-3.82}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"KPTI\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"KPTI\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.2,"buy":0.6,"hold":0.2,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.6,"analysts":5,"updateTime":1785556800000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/KPTI\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"KPTI","date":"2026-09-10","current":-0.123074,"percent":1,"low":-8.777863,"twenty":-3.263757,"median":-1.096025,"eighty":-0.712317,"high":-0.17056,"avg":-1.790462,"sd":1.433229,"marketCap":38331667},"quantilePoints":[{"date":"2021-09-17","current":-2.204146,"twenty":-6.178113,"median":-4.217056,"eighty":-3.26987,"marketCap":458268362},{"date":"2021-09-24","current":-2.273139,"twenty":-6.178113,"median":-4.217056,"eighty":-3.263434,"marketCap":472612841},{"date":"2021-10-01","current":-2.142415,"twenty":-6.178113,"median":-4.217056,"eighty":-3.244364,"marketCap":445433828},{"date":"2021-10-08","current":-2.069791,"twenty":-6.178113,"median":-4.217056,"eighty":-3.226402,"marketCap":430334376},{"date":"2021-10-15","current":-2.029848,"twenty":-6.178113,"median":-4.217056,"eighty":-3.210185,"marketCap":422029677},{"date":"2021-10-22","current":-1.913649,"twenty":-6.178113,"median":-4.217056,"eighty":-3.210185,"marketCap":397870554},{"date":"2021-10-29","current":-1.982642,"twenty":-6.178113,"median":-4.217056,"eighty":-3.210185,"marketCap":412215034},{"date":"2021-11-05","current":-3.08082,"twenty":-6.178113,"median":-4.217056,"eighty":-3.210185,"marketCap":635354458},{"date":"2021-11-12","current":-3.110126,"twenty":-6.178113,"median":-4.217056,"eighty":-3.191989,"marketCap":641398258},{"date":"2021-11-19","current":-2.773104,"twenty":-6.178113,"median":-4.217056,"eighty":-3.171935,"marketCap":571894559},{"date":"2021-11-26","current":-2.663206,"twenty":-6.178113,"median":-4.217056,"eighty":-3.152248,"marketCap":549230310},{"date":"2021-12-03","current":-2.461725,"twenty":-6.178113,"median":-4.217056,"eighty":-3.122043,"marketCap":507679186},{"date":"2021-12-10","current":-2.194306,"twenty":-6.178113,"median":-4.217056,"eighty":-3.077558,"marketCap":452529513},{"date":"2021-12-17","current":-2.252918,"twenty":-6.178113,"median":-4.217056,"eighty":-3.041599,"marketCap":464617112},{"date":"2021-12-23","current":-2.692512,"twenty":-6.178113,"median":-4.217056,"eighty":-3.015867,"marketCap":555274110},{"date":"2021-12-31","current":-2.35549,"twenty":-6.178113,"median":-4.217056,"eighty":-2.991773,"marketCap":485770412},{"date":"2022-01-07","current":-2.586277,"twenty":-6.177382,"median":-4.216189,"eighty":-2.951041,"marketCap":533365335},{"date":"2022-01-14","current":-2.945279,"twenty":-6.177382,"median":-4.216189,"eighty":-2.925652,"marketCap":607401883},{"date":"2022-01-21","current":-3.033197,"twenty":-6.177382,"median":-4.216189,"eighty":-2.908348,"marketCap":625533283},{"date":"2022-01-28","current":-3.128443,"twenty":-6.177382,"median":-4.216189,"eighty":-2.906995,"marketCap":645175632},{"date":"2022-02-04","current":-3.568037,"twenty":-6.177382,"median":-4.216189,"eighty":-2.906995,"marketCap":735832630},{"date":"2022-02-11","current":-6.238509,"twenty":-6.180304,"median":-4.234673,"eighty":-2.906995,"marketCap":774124120},{"date":"2022-02-18","current":-8.777863,"twenty":-6.208868,"median":-4.248181,"eighty":-2.906995,"marketCap":1089227480},{"date":"2022-02-25","current":-6.403323,"twenty":-6.240007,"median":-4.257032,"eighty":-2.906995,"marketCap":794575540},{"date":"2022-03-04","current":-3.770193,"twenty":-6.251665,"median":-4.26161,"eighty":-2.906995,"marketCap":467835694},{"date":"2022-03-11","current":-4.038125,"twenty":-6.251665,"median":-4.254328,"eighty":-2.906995,"marketCap":501082901},{"date":"2022-03-18","current":-4.58037,"twenty":-6.251665,"median":-4.26161,"eighty":-2.906995,"marketCap":568368914},{"date":"2022-03-25","current":-4.663301,"twenty":-6.251665,"median":-4.282008,"eighty":-2.906995,"marketCap":578659716},{"date":"2022-04-01","current":-5.141752,"twenty":-6.251665,"median":-4.29009,"eighty":-2.906995,"marketCap":638029728},{"date":"2022-04-08","current":-5.184068,"twenty":-6.251665,"median":-4.298174,"eighty":-2.906995,"marketCap":643280680},{"date":"2022-04-14","current":-4.992066,"twenty":-6.251665,"median":-4.351584,"eighty":-2.906995,"marketCap":619455470},{"date":"2022-04-22","current":-4.300857,"twenty":-6.251665,"median":-4.367129,"eighty":-2.906995,"marketCap":533684712},{"date":"2022-04-29","current":-3.904052,"twenty":-6.251665,"median":-4.367129,"eighty":-2.906995,"marketCap":484445944},{"date":"2022-05-06","current":-4.467939,"twenty":-6.251665,"median":-4.381025,"eighty":-2.906995,"marketCap":482863561},{"date":"2022-05-13","current":-3.924144,"twenty":-6.251665,"median":-4.381025,"eighty":-2.906995,"marketCap":424093983},{"date":"2022-05-20","current":-4.276876,"twenty":-6.251665,"median":-4.381025,"eighty":-2.906995,"marketCap":462214791},{"date":"2022-05-27","current":-4.688396,"twenty":-6.251665,"median":-4.393149,"eighty":-2.906995,"marketCap":506689066},{"date":"2022-06-03","current":-4.592865,"twenty":-6.251665,"median":-4.413146,"eighty":-2.906995,"marketCap":496364681},{"date":"2022-06-10","current":-4.041721,"twenty":-6.251665,"median":-4.422403,"eighty":-2.906995,"marketCap":436800919},{"date":"2022-06-17","current":-3.262771,"twenty":-6.251665,"median":-4.422403,"eighty":-2.906995,"marketCap":352617469},{"date":"2022-06-24","current":-3.799218,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":410592864},{"date":"2022-07-01","current":-3.47588,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":375648790},{"date":"2022-07-08","current":-3.858006,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":416946332},{"date":"2022-07-15","current":-3.461183,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":374060423},{"date":"2022-07-22","current":-3.27012,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":353411653},{"date":"2022-07-29","current":-3.123148,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":337527983},{"date":"2022-08-05","current":-3.6068,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":373494962},{"date":"2022-08-12","current":-4.169399,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":431753792},{"date":"2022-08-19","current":-4.21564,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":436542189},{"date":"2022-08-26","current":-3.945901,"twenty":-6.253625,"median":-4.431432,"eighty":-2.906836,"marketCap":408609873},{"date":"2022-09-02","current":-4.038383,"twenty":-6.253625,"median":-4.431432,"eighty":-2.906836,"marketCap":418186667},{"date":"2022-09-09","current":-4.123158,"twenty":-6.253625,"median":-4.431432,"eighty":-2.906836,"marketCap":426965395},{"date":"2022-09-16","current":-3.884246,"twenty":-6.253625,"median":-4.431329,"eighty":-2.906836,"marketCap":402225344},{"date":"2022-09-23","current":-3.391009,"twenty":-6.253625,"median":-4.42241,"eighty":-2.906836,"marketCap":351149110},{"date":"2022-09-30","current":-4.207933,"twenty":-6.253625,"median":-4.419107,"eighty":-2.906836,"marketCap":435744123},{"date":"2022-10-07","current":-4.269588,"twenty":-6.253625,"median":-4.407185,"eighty":-2.906836,"marketCap":442128652},{"date":"2022-10-14","current":-3.691575,"twenty":-6.253625,"median":-4.365357,"eighty":-2.906836,"marketCap":382273690},{"date":"2022-10-21","current":-3.506611,"twenty":-6.253625,"median":-4.320057,"eighty":-2.906836,"marketCap":363120102},{"date":"2022-10-28","current":-3.907367,"twenty":-6.253625,"median":-4.320057,"eighty":-2.906836,"marketCap":404619543},{"date":"2022-11-04","current":-4.368078,"twenty":-6.253625,"median":-4.300857,"eighty":-2.906836,"marketCap":384674823},{"date":"2022-11-11","current":-5.215891,"twenty":-6.253625,"median":-4.300857,"eighty":-2.906836,"marketCap":459337447},{"date":"2022-11-18","current":-4.580032,"twenty":-6.253625,"median":-4.300857,"eighty":-2.906836,"marketCap":403340479},{"date":"2022-11-25","current":-4.552385,"twenty":-6.253625,"median":-4.300857,"eighty":-2.906836,"marketCap":400905828},{"date":"2022-12-02","current":-4.745908,"twenty":-6.253625,"median":-4.300857,"eighty":-2.906836,"marketCap":417948383},{"date":"2022-12-09","current":-4.331217,"twenty":-6.253625,"median":-4.294457,"eighty":-2.906836,"marketCap":381428622},{"date":"2022-12-16","current":-2.85676,"twenty":-6.253625,"median":-4.284224,"eighty":-2.903809,"marketCap":251580580},{"date":"2022-12-23","current":-3.32961,"twenty":-6.253625,"median":-4.284224,"eighty":-2.862041,"marketCap":293222102},{"date":"2022-12-30","current":-4.370917,"twenty":-6.253625,"median":-4.294457,"eighty":-2.862041,"marketCap":384924767},{"date":"2023-01-06","current":-4.512329,"twenty":-6.253625,"median":-4.322002,"eighty":-2.862041,"marketCap":397378216},{"date":"2023-01-13","current":-4.24236,"twenty":-6.253625,"median":-4.320057,"eighty":-2.862041,"marketCap":373603451},{"date":"2023-01-20","current":-4.33235,"twenty":-6.253625,"median":-4.322002,"eighty":-2.862041,"marketCap":381528372},{"date":"2023-01-27","current":-4.088093,"twenty":-6.253625,"median":-4.294457,"eighty":-2.862041,"marketCap":360017871},{"date":"2023-02-03","current":-4.370917,"twenty":-6.253625,"median":-4.284224,"eighty":-2.862041,"marketCap":384924767},{"date":"2023-02-10","current":-4.165226,"twenty":-6.253625,"median":-4.269527,"eighty":-2.862041,"marketCap":366810661},{"date":"2023-02-17","current":-2.43428,"twenty":-6.240783,"median":-4.262179,"eighty":-2.84267,"marketCap":402364561},{"date":"2023-02-24","current":-2.057138,"twenty":-6.238604,"median":-4.24236,"eighty":-2.823533,"marketCap":340026390},{"date":"2023-03-03","current":-2.146281,"twenty":-6.180304,"median":-4.224661,"eighty":-2.781626,"marketCap":354760866},{"date":"2023-03-10","current":-2.057138,"twenty":-6.152907,"median":-4.208959,"eighty":-2.75484,"marketCap":340026390},{"date":"2023-03-17","current":-2.331423,"twenty":-6.11274,"median":-4.196041,"eighty":-2.706336,"marketCap":385363242},{"date":"2023-03-24","current":-2.276566,"twenty":-6.11274,"median":-4.183771,"eighty":-2.661741,"marketCap":376295871},{"date":"2023-03-31","current":-2.667422,"twenty":-6.111964,"median":-4.173741,"eighty":-2.649856,"marketCap":440900885},{"date":"2023-04-06","current":-2.681136,"twenty":-6.111964,"median":-4.146073,"eighty":-2.649856,"marketCap":443167728},{"date":"2023-04-14","current":-2.978326,"twenty":-6.11274,"median":-4.128054,"eighty":-2.647561,"marketCap":492290498},{"date":"2023-04-21","current":-2.619824,"twenty":-6.11274,"median":-4.108854,"eighty":-2.641981,"marketCap":433033309},{"date":"2023-04-28","current":-2.412996,"twenty":-6.11274,"median":-4.086917,"eighty":-2.626336,"marketCap":398846469},{"date":"2023-05-05","current":-1.997872,"twenty":-6.087907,"median":-4.049743,"eighty":-2.6213,"marketCap":315699670},{"date":"2023-05-12","current":-1.911983,"twenty":-6.00906,"median":-4.038383,"eighty":-2.601613,"marketCap":302127687},{"date":"2023-05-19","current":-1.738822,"twenty":-5.954697,"median":-4.012327,"eighty":-2.595069,"marketCap":274765179},{"date":"2023-05-26","current":-1.738822,"twenty":-5.924166,"median":-3.998811,"eighty":-2.559679,"marketCap":274765179},{"date":"2023-06-02","current":-1.587306,"twenty":-5.912525,"median":-3.987794,"eighty":-2.54416,"marketCap":250822985},{"date":"2023-06-09","current":-1.688317,"twenty":-5.903664,"median":-3.97614,"eighty":-2.515942,"marketCap":266784448},{"date":"2023-06-16","current":-1.493511,"twenty":-5.881585,"median":-3.961315,"eighty":-2.495534,"marketCap":236001627},{"date":"2023-06-23","current":-1.464651,"twenty":-5.820152,"median":-3.946448,"eighty":-2.476356,"marketCap":231441209},{"date":"2023-06-30","current":-1.32035,"twenty":-5.781367,"median":-3.938194,"eighty":-2.46815,"marketCap":208639119},{"date":"2023-07-07","current":-1.096684,"twenty":-5.767239,"median":-3.926795,"eighty":-2.461725,"marketCap":173295880},{"date":"2023-07-14","current":-1.183265,"twenty":-5.753441,"median":-3.916124,"eighty":-2.45079,"marketCap":186977134},{"date":"2023-07-21","current":-1.16162,"twenty":-5.738623,"median":-3.902098,"eighty":-2.423309,"marketCap":183556821},{"date":"2023-07-28","current":-1.21934,"twenty":-5.710966,"median":-3.89966,"eighty":-2.39588,"marketCap":192677657},{"date":"2023-08-04","current":-1.46188,"twenty":-5.691895,"median":-3.884246,"eighty":-2.372906,"marketCap":206981717},{"date":"2023-08-11","current":-1.348806,"twenty":-5.675808,"median":-3.862584,"eighty":-2.346821,"marketCap":190972081},{"date":"2023-08-18","current":-1.356883,"twenty":-5.661094,"median":-3.856444,"eighty":-2.327554,"marketCap":192115627},{"date":"2023-08-25","current":-1.122659,"twenty":-5.642939,"median":-3.835297,"eighty":-2.279163,"marketCap":158952810},{"date":"2023-09-01","current":-1.033816,"twenty":-5.621148,"median":-3.822591,"eighty":-2.226817,"marketCap":146373811},{"date":"2023-09-08","current":-0.936895,"twenty":-5.610619,"median":-3.805269,"eighty":-2.211408,"marketCap":132651266},{"date":"2023-09-15","current":-1.049969,"twenty":-5.594688,"median":-3.791764,"eighty":-2.194285,"marketCap":148660902},{"date":"2023-09-22","current":-1.009586,"twenty":-5.573404,"median":-3.784057,"eighty":-2.163015,"marketCap":142943175},{"date":"2023-09-29","current":-1.106506,"twenty":-5.553533,"median":-3.768644,"eighty":-2.142415,"marketCap":156665719},{"date":"2023-10-06","current":-1.058046,"twenty":-5.535997,"median":-3.751711,"eighty":-2.124259,"marketCap":149804447},{"date":"2023-10-13","current":-1.009586,"twenty":-5.530362,"median":-3.745537,"eighty":-2.113365,"marketCap":142943175},{"date":"2023-10-20","current":-0.856129,"twenty":-5.528881,"median":-3.711035,"eighty":-2.099567,"marketCap":121215812},{"date":"2023-10-27","current":-0.647104,"twenty":-5.530246,"median":-3.695288,"eighty":-2.090126,"marketCap":91620857},{"date":"2023-11-03","current":-0.622876,"twenty":-5.530246,"median":-3.680928,"eighty":-2.070428,"marketCap":87058111},{"date":"2023-11-10","current":-0.56813,"twenty":-5.530246,"median":-3.667547,"eighty":-2.054937,"marketCap":79406415},{"date":"2023-11-17","current":-0.570752,"twenty":-5.530246,"median":-3.644676,"eighty":-2.02705,"marketCap":79772924},{"date":"2023-11-24","current":-0.605088,"twenty":-5.530246,"median":-3.63006,"eighty":-2.008787,"marketCap":84571898},{"date":"2023-12-01","current":-0.630983,"twenty":-5.530246,"median":-3.594199,"eighty":-1.984272,"marketCap":88191173},{"date":"2023-12-08","current":-0.687115,"twenty":-5.530188,"median":-3.575973,"eighty":-1.952485,"marketCap":96036751},{"date":"2023-12-15","current":-0.688509,"twenty":-5.530188,"median":-3.560803,"eighty":-1.928904,"marketCap":96231459},{"date":"2023-12-22","current":-0.62328,"twenty":-5.530188,"median":-3.557127,"eighty":-1.913316,"marketCap":87114553},{"date":"2023-12-29","current":-0.756605,"twenty":-5.530246,"median":-3.558965,"eighty":-1.898992,"marketCap":105749233},{"date":"2024-01-05","current":-0.676053,"twenty":-5.530304,"median":-3.549366,"eighty":-1.893314,"marketCap":94490542},{"date":"2024-01-12","current":-0.604924,"twenty":-5.530304,"median":-3.523541,"eighty":-1.878246,"marketCap":84548992},{"date":"2024-01-19","current":-0.593206,"twenty":-5.530362,"median":-3.503855,"eighty":-1.861175,"marketCap":82911156},{"date":"2024-01-26","current":-0.717599,"twenty":-5.530304,"median":-3.501098,"eighty":-1.83927,"marketCap":100297415},{"date":"2024-02-02","current":-0.737758,"twenty":-5.530304,"median":-3.501098,"eighty":-1.821001,"marketCap":103114952},{"date":"2024-02-09","current":-1.237381,"twenty":-5.530304,"median":-3.501098,"eighty":-1.803757,"marketCap":172946326},{"date":"2024-02-16","current":-1.065295,"twenty":-5.530304,"median":-3.497357,"eighty":-1.784998,"marketCap":148894188},{"date":"2024-02-23","current":-0.925987,"twenty":-5.530304,"median":-3.493617,"eighty":-1.76886,"marketCap":129423409},{"date":"2024-03-01","current":-0.931533,"twenty":-5.530246,"median":-3.493617,"eighty":-1.765064,"marketCap":133301400},{"date":"2024-03-08","current":-1.230286,"twenty":-5.530246,"median":-3.493617,"eighty":-1.765064,"marketCap":176052636},{"date":"2024-03-15","current":-1.077505,"twenty":-5.530246,"median":-3.493617,"eighty":-1.765064,"marketCap":154189891},{"date":"2024-03-22","current":-1.141834,"twenty":-5.530246,"median":-3.493617,"eighty":-1.75222,"marketCap":163395257},{"date":"2024-03-28","current":-1.19008,"twenty":-5.530246,"median":-3.493617,"eighty":-1.741713,"marketCap":170299282},{"date":"2024-04-05","current":-1.069464,"twenty":-5.530304,"median":-3.493617,"eighty":-1.717331,"marketCap":153039220},{"date":"2024-04-12","current":-1.077505,"twenty":-5.530304,"median":-3.493617,"eighty":-1.708028,"marketCap":154189891},{"date":"2024-04-19","current":-1.041769,"twenty":-5.530304,"median":-3.493617,"eighty":-1.692185,"marketCap":149076142},{"date":"2024-04-26","current":-0.862715,"twenty":-5.530246,"median":-3.493617,"eighty":-1.684206,"marketCap":123453680},{"date":"2024-05-03","current":-0.878993,"twenty":-5.530246,"median":-3.493617,"eighty":-1.684206,"marketCap":125782994},{"date":"2024-05-10","current":-0.860696,"twenty":-5.530246,"median":-3.493617,"eighty":-1.684206,"marketCap":125949981},{"date":"2024-05-17","current":-0.912982,"twenty":-5.530246,"median":-3.493617,"eighty":-1.684206,"marketCap":133601148},{"date":"2024-05-24","current":-0.876784,"twenty":-5.530246,"median":-3.493617,"eighty":-1.679677,"marketCap":128304186},{"date":"2024-05-31","current":-0.807467,"twenty":-5.530246,"median":-3.493617,"eighty":-1.663086,"marketCap":118160637},{"date":"2024-06-07","current":-0.828501,"twenty":-5.530246,"median":-3.493617,"eighty":-1.652426,"marketCap":121238645},{"date":"2024-06-14","current":-0.86861,"twenty":-5.530304,"median":-3.493617,"eighty":-1.621772,"marketCap":127108046},{"date":"2024-06-21","current":-0.807575,"twenty":-5.530362,"median":-3.495487,"eighty":-1.552674,"marketCap":118176450},{"date":"2024-06-28","current":-0.828782,"twenty":-5.531765,"median":-3.501098,"eighty":-1.502169,"marketCap":121279797},{"date":"2024-07-05","current":-0.705372,"twenty":-5.531765,"median":-3.501098,"eighty":-1.463543,"marketCap":103220561},{"date":"2024-07-12","current":-0.819669,"twenty":-5.531765,"median":-3.501098,"eighty":-1.430073,"marketCap":119946230},{"date":"2024-07-15","current":-0.803572,"twenty":-5.531765,"median":-3.501098,"eighty":-1.408574,"marketCap":117590677},{"date":"2024-08-02","current":-0.786708,"twenty":-5.540395,"median":-3.52844,"eighty":-1.378071,"marketCap":115122956},{"date":"2024-08-09","current":-1.162622,"twenty":-5.540395,"median":-3.52844,"eighty":-1.348806,"marketCap":104534798},{"date":"2024-08-16","current":-1.156659,"twenty":-5.540395,"median":-3.52844,"eighty":-1.300346,"marketCap":103998658},{"date":"2024-08-23","current":-1.091622,"twenty":-5.540395,"median":-3.52844,"eighty":-1.26245,"marketCap":98150993},{"date":"2024-08-30","current":-1.06888,"twenty":-5.540395,"median":-3.52844,"eighty":-1.237381,"marketCap":96106181},{"date":"2024-09-06","current":-1.106182,"twenty":-5.540395,"median":-3.52844,"eighty":-1.214203,"marketCap":99460172},{"date":"2024-09-13","current":-1.020345,"twenty":-5.540395,"median":-3.52844,"eighty":-1.19008,"marketCap":91742252},{"date":"2024-09-20","current":-1.024921,"twenty":-5.540395,"median":-3.52844,"eighty":-1.179196,"marketCap":92153708},{"date":"2024-09-27","current":-0.979714,"twenty":-5.540395,"median":-3.52844,"eighty":-1.162622,"marketCap":88089020},{"date":"2024-10-04","current":-1.221696,"twenty":-5.540395,"median":-3.52844,"eighty":-1.156659,"marketCap":109846322},{"date":"2024-10-11","current":-1.174547,"twenty":-5.540395,"median":-3.52844,"eighty":-1.156659,"marketCap":105607077},{"date":"2024-10-18","current":-1.184254,"twenty":-5.540395,"median":-3.52844,"eighty":-1.156659,"marketCap":106479863},{"date":"2024-10-25","current":-1.131559,"twenty":-5.540395,"median":-3.52844,"eighty":-1.155827,"marketCap":101741883},{"date":"2024-10-31","current":-1.165118,"twenty":-5.540395,"median":-3.52844,"eighty":-1.155436,"marketCap":104759228},{"date":"2024-11-08","current":-1.26376,"twenty":-5.541296,"median":-3.5198,"eighty":-1.15523,"marketCap":110552457},{"date":"2024-11-15","current":-1.19944,"twenty":-5.541296,"median":-3.493617,"eighty":-1.15523,"marketCap":104925835},{"date":"2024-11-22","current":-1.113919,"twenty":-5.541296,"median":-3.47588,"eighty":-1.14719,"marketCap":97444559},{"date":"2024-11-29","current":-1.210614,"twenty":-5.541296,"median":-3.463693,"eighty":-1.14719,"marketCap":105903289},{"date":"2024-12-06","current":-1.140851,"twenty":-5.541296,"median":-3.43751,"eighty":-1.145928,"marketCap":99800472},{"date":"2024-12-13","current":-1.037137,"twenty":-5.541296,"median":-3.414129,"eighty":-1.13842,"marketCap":90727702},{"date":"2024-12-20","current":-0.930558,"twenty":-5.537319,"median":-3.387697,"eighty":-1.128401,"marketCap":81404303},{"date":"2024-12-27","current":-0.859506,"twenty":-5.530188,"median":-3.36644,"eighty":-1.123123,"marketCap":75188703},{"date":"2025-01-03","current":-1.162625,"twenty":-5.516937,"median":-3.343606,"eighty":-1.121478,"marketCap":101705253},{"date":"2025-01-10","current":-1.025677,"twenty":-5.508837,"median":-3.312909,"eighty":-1.11771,"marketCap":89725186},{"date":"2025-01-17","current":-1.007316,"twenty":-5.497414,"median":-3.305436,"eighty":-1.112429,"marketCap":88118996},{"date":"2025-01-24","current":-0.992746,"twenty":-5.497414,"median":-3.273794,"eighty":-1.107,"marketCap":86844470},{"date":"2025-01-31","current":-0.957982,"twenty":-5.497414,"median":-3.261546,"eighty":-1.105896,"marketCap":83803273},{"date":"2025-02-07","current":-0.94774,"twenty":-5.497414,"median":-3.175832,"eighty":-1.099644,"marketCap":82907318},{"date":"2025-02-14","current":-0.879508,"twenty":-5.497414,"median":-3.156988,"eighty":-1.094654,"marketCap":76938496},{"date":"2025-02-21","current":-1.007647,"twenty":-5.497414,"median":-3.135466,"eighty":-1.083557,"marketCap":77006432},{"date":"2025-02-28","current":-0.919547,"twenty":-5.497414,"median":-3.112977,"eighty":-1.076519,"marketCap":70273658},{"date":"2025-03-07","current":-0.68498,"twenty":-5.459269,"median":-3.063461,"eighty":-1.066729,"marketCap":52347563},{"date":"2025-03-14","current":-0.764271,"twenty":-5.377449,"median":-3.033537,"eighty":-1.058663,"marketCap":58407088},{"date":"2025-03-21","current":-0.67617,"twenty":-5.323498,"median":-2.978326,"eighty":-1.050101,"marketCap":51674282},{"date":"2025-03-28","current":-0.479046,"twenty":-5.224446,"median":-2.945279,"eighty":-1.041892,"marketCap":36609630},{"date":"2025-04-04","current":-0.425084,"twenty":-5.182452,"median":-2.90636,"eighty":-1.037854,"marketCap":32485787},{"date":"2025-04-11","current":-0.439401,"twenty":-5.097768,"median":-2.855494,"eighty":-1.033601,"marketCap":33579867},{"date":"2025-04-17","current":-0.486754,"twenty":-4.988131,"median":-2.820242,"eighty":-1.024311,"marketCap":37198750},{"date":"2025-04-25","current":-0.657449,"twenty":-4.90474,"median":-2.783037,"eighty":-1.019651,"marketCap":50243561},{"date":"2025-05-02","current":-0.758085,"twenty":-4.802193,"median":-2.732808,"eighty":-1.010806,"marketCap":57934396},{"date":"2025-05-09","current":-0.689678,"twenty":-4.756262,"median":-2.687994,"eighty":-1.007448,"marketCap":52706588},{"date":"2025-05-16","current":-0.745686,"twenty":-4.690954,"median":-2.666869,"eighty":-1.002814,"marketCap":46621762},{"date":"2025-05-23","current":-0.641201,"twenty":-4.668631,"median":-2.639443,"eighty":-0.991544,"marketCap":40089154},{"date":"2025-05-30","current":-0.626,"twenty":-4.606093,"median":-2.61192,"eighty":-0.988921,"marketCap":39138765},{"date":"2025-06-06","current":-0.588689,"twenty":-4.57934,"median":-2.571624,"eighty":-0.98354,"marketCap":36805991},{"date":"2025-06-13","current":-0.602508,"twenty":-4.544148,"median":-2.497361,"eighty":-0.976077,"marketCap":37669981},{"date":"2025-06-20","current":-0.613563,"twenty":-4.525095,"median":-2.464938,"eighty":-0.968885,"marketCap":38361173},{"date":"2025-06-27","current":-0.620472,"twenty":-4.496165,"median":-2.44341,"eighty":-0.961125,"marketCap":38793168},{"date":"2025-07-03","current":-0.606653,"twenty":-4.462711,"median":-2.413709,"eighty":-0.955525,"marketCap":37929178},{"date":"2025-07-11","current":-0.690949,"twenty":-4.419353,"median":-2.38628,"eighty":-0.94965,"marketCap":43199520},{"date":"2025-07-18","current":-0.562433,"twenty":-4.370917,"median":-2.350313,"eighty":-0.944972,"marketCap":35164409},{"date":"2025-07-25","current":-0.612181,"twenty":-4.34425,"median":-2.283059,"eighty":-0.930753,"marketCap":38274774},{"date":"2025-08-01","current":-0.526503,"twenty":-4.321613,"median":-2.22019,"eighty":-0.921603,"marketCap":32918034},{"date":"2025-08-08","current":-0.548614,"twenty":-4.291871,"median":-2.206071,"eighty":-0.917005,"marketCap":34300418},{"date":"2025-08-15","current":-0.326315,"twenty":-4.268071,"median":-2.187423,"eighty":-0.909097,"marketCap":40321442},{"date":"2025-08-22","current":-0.422455,"twenty":-4.25249,"median":-2.149795,"eighty":-0.897627,"marketCap":52201093},{"date":"2025-08-29","current":-0.538946,"twenty":-4.228811,"median":-2.135675,"eighty":-0.890144,"marketCap":66595415},{"date":"2025-09-05","current":-0.47263,"twenty":-4.21564,"median":-2.12104,"eighty":-0.879508,"marketCap":58401057},{"date":"2025-09-12","current":-0.465964,"twenty":-4.197295,"median":-2.11268,"eighty":-0.876852,"marketCap":57577285},{"date":"2025-09-19","current":-0.402104,"twenty":-4.178393,"median":-2.097025,"eighty":-0.869983,"marketCap":49686422},{"date":"2025-09-26","current":-0.467367,"twenty":-4.162571,"median":-2.082501,"eighty":-0.859744,"marketCap":57750711},{"date":"2025-10-03","current":-0.441402,"twenty":-4.136838,"median":-2.059833,"eighty":-0.852257,"marketCap":54542338},{"date":"2025-10-10","current":-0.40842,"twenty":-4.110409,"median":-2.031663,"eighty":-0.841527,"marketCap":50466837},{"date":"2025-10-17","current":-0.423157,"twenty":-4.087399,"median":-2.015323,"eighty":-0.828364,"marketCap":52287806},{"date":"2025-10-24","current":-0.434385,"twenty":-4.048591,"median":-1.980827,"eighty":-0.8194,"marketCap":53675210},{"date":"2025-10-31","current":-0.768209,"twenty":-4.035263,"median":-1.924543,"eighty":-0.814808,"marketCap":94924556},{"date":"2025-11-07","current":-0.71421,"twenty":-4.001921,"median":-1.893677,"eighty":-0.800042,"marketCap":89005572},{"date":"2025-11-14","current":-0.75252,"twenty":-3.983807,"median":-1.863937,"eighty":-0.787249,"marketCap":93779818},{"date":"2025-11-21","current":-0.788094,"twenty":-3.966625,"median":-1.80015,"eighty":-0.784283,"marketCap":98213045},{"date":"2025-11-28","current":-0.768939,"twenty":-3.952294,"median":-1.769857,"eighty":-0.774404,"marketCap":95825923},{"date":"2025-12-05","current":-0.808617,"twenty":-3.936806,"median":-1.738822,"eighty":-0.768355,"marketCap":100770677},{"date":"2025-12-12","current":-0.957753,"twenty":-3.920106,"median":-1.702747,"eighty":-0.768355,"marketCap":119356132},{"date":"2025-12-19","current":-0.871555,"twenty":-3.906704,"median":-1.645027,"eighty":-0.768355,"marketCap":108614080},{"date":"2025-12-26","current":-1.022059,"twenty":-3.900594,"median":-1.598129,"eighty":-0.768355,"marketCap":127370043},{"date":"2026-01-02","current":-1.007009,"twenty":-3.882973,"median":-1.518763,"eighty":-0.768355,"marketCap":125494447},{"date":"2026-01-09","current":-1.2004,"twenty":-3.860185,"median":-1.463265,"eighty":-0.768355,"marketCap":149595012},{"date":"2026-01-16","current":-0.978539,"twenty":-3.835167,"median":-1.428644,"eighty":-0.768355,"marketCap":121946484},{"date":"2026-01-23","current":-0.9756,"twenty":-3.827408,"median":-1.378071,"eighty":-0.768355,"marketCap":121580279},{"date":"2026-01-30","current":-0.974131,"twenty":-3.803157,"median":-1.352845,"eighty":-0.768355,"marketCap":121397176},{"date":"2026-02-06","current":-0.89479,"twenty":-3.785183,"median":-1.314386,"eighty":-0.768355,"marketCap":111509623},{"date":"2026-02-13","current":-0.835007,"twenty":-3.775776,"median":-1.289956,"eighty":-0.768355,"marketCap":163693930},{"date":"2026-02-20","current":-0.904851,"twenty":-3.76825,"median":-1.270277,"eighty":-0.768355,"marketCap":177386170},{"date":"2026-02-27","current":-0.874908,"twenty":-3.750555,"median":-1.253537,"eighty":-0.768355,"marketCap":171516100},{"date":"2026-03-06","current":-0.825314,"twenty":-3.712954,"median":-1.240985,"eighty":-0.768355,"marketCap":161793797},{"date":"2026-03-13","current":-0.739227,"twenty":-3.688987,"median":-1.228001,"eighty":-0.765509,"marketCap":144917347},{"date":"2026-03-20","current":-0.72332,"twenty":-3.668455,"median":-1.212409,"eighty":-0.761437,"marketCap":141798872},{"date":"2026-03-27","current":-0.557402,"twenty":-3.6487,"median":-1.205909,"eighty":-0.756677,"marketCap":109272438},{"date":"2026-04-02","current":-0.669265,"twenty":-3.625972,"median":-1.19992,"eighty":-0.747155,"marketCap":131202099},{"date":"2026-04-10","current":-0.938351,"twenty":-3.584639,"median":-1.19048,"eighty":-0.745958,"marketCap":183953458},{"date":"2026-04-17","current":-0.995848,"twenty":-3.563174,"median":-1.18618,"eighty":-0.745958,"marketCap":195225116},{"date":"2026-04-24","current":-1.006198,"twenty":-3.529112,"median":-1.182503,"eighty":-0.745958,"marketCap":197254015},{"date":"2026-05-01","current":-0.9556,"twenty":-3.517162,"median":-1.1762,"eighty":-0.745958,"marketCap":187334955},{"date":"2026-05-08","current":-1.017697,"twenty":-3.505508,"median":-1.167532,"eighty":-0.745958,"marketCap":199508346},{"date":"2026-05-15","current":-1.023807,"twenty":-3.505508,"median":-1.162834,"eighty":-0.745958,"marketCap":200706125},{"date":"2026-05-22","current":-0.932267,"twenty":-3.496609,"median":-1.161289,"eighty":-0.745958,"marketCap":181763075},{"date":"2026-05-29","current":-1.053716,"twenty":-3.497357,"median":-1.155827,"eighty":-0.745686,"marketCap":205441887},{"date":"2026-06-05","current":-1.049089,"twenty":-3.496609,"median":-1.149081,"eighty":-0.745958,"marketCap":204539837},{"date":"2026-06-12","current":-1.040992,"twenty":-3.460937,"median":-1.141342,"eighty":-0.745958,"marketCap":202961250},{"date":"2026-06-18","current":-1.092644,"twenty":-3.431873,"median":-1.136983,"eighty":-0.745958,"marketCap":213031664},{"date":"2026-06-26","current":-1.099618,"twenty":-3.381209,"median":-1.125752,"eighty":-0.745686,"marketCap":214391440},{"date":"2026-07-02","current":-1.11008,"twenty":-3.358303,"median":-1.125545,"eighty":-0.745686,"marketCap":216431105},{"date":"2026-07-10","current":-1.185635,"twenty":-3.314211,"median":-1.123239,"eighty":-0.745686,"marketCap":231162018},{"date":"2026-07-17","current":-1.090319,"twenty":-3.30428,"median":-1.122268,"eighty":-0.745686,"marketCap":212578405},{"date":"2026-07-24","current":-0.824132,"twenty":-3.267699,"median":-1.11771,"eighty":-0.745686,"marketCap":160680265},{"date":"2026-07-31","current":-0.814833,"twenty":-3.263757,"median":-1.115455,"eighty":-0.745685,"marketCap":158867230},{"date":"2026-08-07","current":-0.226665,"twenty":-3.263757,"median":-1.110137,"eighty":-0.741781,"marketCap":44192738},{"date":"2026-08-14","current":-0.200837,"twenty":-3.263757,"median":-1.106918,"eighty":-0.738013,"marketCap":45136105},{"date":"2026-08-21","current":-0.18368,"twenty":-3.263757,"median":-1.105825,"eighty":-0.729154,"marketCap":41280257},{"date":"2026-08-28","current":-0.195791,"twenty":-3.263757,"median":-1.101041,"eighty":-0.720727,"marketCap":44002032},{"date":"2026-09-04","current":-0.178634,"twenty":-3.263757,"median":-1.098311,"eighty":-0.71416,"marketCap":40146184},{"date":"2026-09-10","current":-0.17056,"twenty":-3.263757,"median":-1.096025,"eighty":-0.712317,"marketCap":38331667}],"updateTime":1789164218522},"$inf$@#url:\"https://stock-news.skytigris.cn/v3/notice/important/events/list\",params:#symbol:\"KPTI\",pageSize:20,pageCount:8,market:\"us\",,,undefined,":[{"items":[{"cdn_pdf":false,"hasAttachments":false,"id":"12949168","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312521197924-KPTI","pdf_url":null,"pub_time":1624464000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"KPTI","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521197924/0001193125-21-197924-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 1.01: Entry into a Material Definitive Agreement;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2021-06-24 00:00","pubTimestamp":1624464000,"title_zh":"8-K  - Current report","summary_en":"Item 1.01: Entry into a Material Definitive Agreement;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"12791432","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312521170821-KPTI","pdf_url":null,"pub_time":1621785600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"KPTI","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521170821/0001193125-21-170821-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 5.07: Submission of Matters to a Vote of Security Holders","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521170821/d107005d8k.htm","primary":true,"translateUrl":null,"linkName":"d107005d8k.htm","type":"8-K","id":"NTFILE5A4meRBNwr6PFQsx","market":"us","size":34760}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2021-05-24 00:00","pubTimestamp":1621785600,"title_zh":"8-K  - Current report","summary_en":"Item 5.07: Submission of Matters to a Vote of Security Holders","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"12685396","market":"us","labels":[],"media":"sec.gov","original_id":"AN95017021000073-KPTI","pdf_url":null,"pub_time":1620057600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"10-Q  - Quarterly report [Sections 13 or 15(d)]","symbol":"KPTI","title":"10-Q  - Quarterly report [Sections 13 or 15(d)]","titleType":"Quarterly Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1503802/000095017021000073/0000950170-21-000073-index.htm","us_notice_code":"Form 10-Q","us_title_en":"10-Q  - Quarterly report [Sections 13 or 15(d)]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-Q","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000095017021000073/kpti-20210331.htm","primary":true,"translateUrl":null,"linkName":"kpti-20210331.htm","type":"10-Q","id":"NTFILE9LtHDvZa7vW7rgZb","market":"us","size":1940244},{"description":"EX-31.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000095017021000073/kpti-20210331-ex31_1.htm","primary":false,"translateUrl":null,"linkName":"kpti-20210331-ex31_1.htm","type":"EX-31.1","id":"NTFILE4CCzpdYAPAdJBb4o","market":"us","size":11412},{"description":"EX-31.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000095017021000073/kpti-20210331-ex31_2.htm","primary":false,"translateUrl":null,"linkName":"kpti-20210331-ex31_2.htm","type":"EX-31.2","id":"NTFILE8FpKjVUgTC7FTx85","market":"us","size":11449},{"description":"EX-32.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000095017021000073/kpti-20210331-ex32_1.htm","primary":false,"translateUrl":null,"linkName":"kpti-20210331-ex32_1.htm","type":"EX-32.1","id":"NTFILEAqR8E3Rz9QFtWQW5","market":"us","size":6407},{"description":"EX-32.2","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000095017021000073/kpti-20210331-ex32_2.htm","primary":false,"translateUrl":null,"linkName":"kpti-20210331-ex32_2.htm","type":"EX-32.2","id":"NTFILEEmWKadabSv94Dbog","market":"us","size":6732}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Quarterly Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Quarterly Report","pubTime":"2021-05-04 00:00","pubTimestamp":1620057600,"title_zh":"10-Q  - Quarterly report [Sections 13 or 15(d","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"12680058","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312521146627-KPTI","pdf_url":null,"pub_time":1619971200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"KPTI","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521146627/0001193125-21-146627-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521146627/d160181dex991.htm","primary":true,"translateUrl":null,"linkName":"d160181dex991.htm","type":"EX-99.1","id":"NTFILE2LwF9nsAtyV2Z1iH","market":"us","size":93921},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521146627/d160181d8k.htm","primary":false,"translateUrl":null,"linkName":"d160181d8k.htm","type":"8-K","id":"NTFILEDr9xDQKhaBD8DbbF","market":"us","size":25775},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521146627/g160181g12o29.jpg","primary":false,"translateUrl":null,"linkName":"g160181g12o29.jpg","type":"GRAPHIC","id":"NTFILECsbsoBQCzTzveiQq","market":"us","size":4019}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2021-05-03 00:00","pubTimestamp":1619971200,"title_zh":"8-K  - Current report","summary_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"12680057","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312521146624-KPTI","pdf_url":null,"pub_time":1619971200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"KPTI","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521146624/0001193125-21-146624-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 5.02: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-10.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521146624/d172053dex101.htm","primary":true,"translateUrl":null,"linkName":"d172053dex101.htm","type":"EX-10.1","id":"NTFILEC18bP4eqK5MJkf2z","market":"us","size":44491},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521146624/d172053d8k.htm","primary":false,"translateUrl":null,"linkName":"d172053d8k.htm","type":"8-K","id":"NTFILEHLwsr47VBBp3fxHd","market":"us","size":44810},{"description":"EX-10.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521146624/d172053dex102.htm","primary":false,"translateUrl":null,"linkName":"d172053dex102.htm","type":"EX-10.2","id":"NTFILEFv6mDoMty7ibKfut","market":"us","size":51374},{"description":"EX-10.3","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521146624/d172053dex103.htm","primary":false,"translateUrl":null,"linkName":"d172053dex103.htm","type":"EX-10.3","id":"NTFILE55DAQGKW3imgYRiA","market":"us","size":54083},{"description":"GRAPHIC","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521146624/g172053karyopharm.jpg","primary":false,"translateUrl":null,"linkName":"g172053karyopharm.jpg","type":"GRAPHIC","id":"NTFILE9tnDT8eQmCsqyJzA","market":"us","size":4560}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2021-05-03 00:00","pubTimestamp":1619971200,"title_zh":"8-K  - Current report","summary_en":"Item 5.02: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11960704","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312521054879-KPTI","pdf_url":null,"pub_time":1614096000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"S-8  - Securities to be offered to employees in employee benefit plans","symbol":"KPTI","title":"S-8  - Securities to be offered to employees in employee benefit plans","titleType":"Employee Stock Ownership","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054879/0001193125-21-054879-index.htm","us_notice_code":"Form S-8","us_title_en":"S-8  - Securities to be offered to employees in employee benefit plans","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"S-8","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054879/d36778ds8.htm","primary":true,"translateUrl":null,"linkName":"d36778ds8.htm","type":"S-8","id":"NTFILEFCkK2JEiGTLixN4a","market":"us","size":37879},{"description":"EX-5.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054879/d36778dex51.htm","primary":false,"translateUrl":null,"linkName":"d36778dex51.htm","type":"EX-5.1","id":"NTFILE2uRZMEwSRLMRVWhE","market":"us","size":7621},{"description":"EX-23.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054879/d36778dex232.htm","primary":false,"translateUrl":null,"linkName":"d36778dex232.htm","type":"EX-23.2","id":"NTFILE8bTLGYwmA3wK1LRr","market":"us","size":1622},{"description":"GRAPHIC","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054879/g36778g0223205247787.jpg","primary":false,"translateUrl":null,"linkName":"g36778g0223205247787.jpg","type":"GRAPHIC","id":"NTFILE3tPzm8Kvv9sGgKF4","market":"us","size":3373},{"description":"GRAPHIC","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054879/g36778g0223205247943.jpg","primary":false,"translateUrl":null,"linkName":"g36778g0223205247943.jpg","type":"GRAPHIC","id":"NTFILEBwECbXjEUbZSAhxy","market":"us","size":5074}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Employee Stock Ownership","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Employee Stock Ownership","pubTime":"2021-02-24 00:00","pubTimestamp":1614096000,"title_zh":"S-8  - Securities to be offered to employees in employee benefit plans","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11960703","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312521054811-KPTI","pdf_url":null,"pub_time":1614096000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","symbol":"KPTI","title":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","titleType":"Annual Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054811/0001193125-21-054811-index.htm","us_notice_code":"Form 10-K","us_title_en":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054811/d53064d10k.htm","primary":true,"translateUrl":null,"linkName":"d53064d10k.htm","type":"10-K","id":"NTFILE4Wwo6LazHn5gghqp","market":"us","size":2724211},{"description":"EX-4.3","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054811/d53064dex43.htm","primary":false,"translateUrl":null,"linkName":"d53064dex43.htm","type":"EX-4.3","id":"NTFILE6jQ4HZyQQ7BJpaE9","market":"us","size":15763},{"description":"EX-21.1","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054811/d53064dex211.htm","primary":false,"translateUrl":null,"linkName":"d53064dex211.htm","type":"EX-21.1","id":"NTFILEAKwLDDvMPmKfHY9a","market":"us","size":1938},{"description":"EX-23.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054811/d53064dex231.htm","primary":false,"translateUrl":null,"linkName":"d53064dex231.htm","type":"EX-23.1","id":"NTFILE5ZaEEbqokKFVijGk","market":"us","size":7053},{"description":"EX-31.1","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054811/d53064dex311.htm","primary":false,"translateUrl":null,"linkName":"d53064dex311.htm","type":"EX-31.1","id":"NTFILEF2Qic4GW7wYiMEku","market":"us","size":6362},{"description":"EX-31.2","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054811/d53064dex312.htm","primary":false,"translateUrl":null,"linkName":"d53064dex312.htm","type":"EX-31.2","id":"NTFILEDwGxfESuP2g6Pkvb","market":"us","size":6355},{"description":"EX-32.1","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054811/d53064dex321.htm","primary":false,"translateUrl":null,"linkName":"d53064dex321.htm","type":"EX-32.1","id":"NTFILE4tRi8zwk3YKa9pXe","market":"us","size":4336},{"description":"GRAPHIC","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054811/g53064g56e40.jpg","primary":false,"translateUrl":null,"linkName":"g53064g56e40.jpg","type":"GRAPHIC","id":"NTFILE81oqGSEzV4jhCFHf","market":"us","size":196297},{"description":"GRAPHIC","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521054811/g53064g78p30.jpg","primary":false,"translateUrl":null,"linkName":"g53064g78p30.jpg","type":"GRAPHIC","id":"NTFILE1NDdsMMkMHYZWKp9","market":"us","size":121005}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Annual Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Annual Report","pubTime":"2021-02-24 00:00","pubTimestamp":1614096000,"title_zh":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11880623","market":"us","labels":[],"media":"sec.gov","original_id":"AN108514621001037-KPTI","pdf_url":null,"pub_time":1613491200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","symbol":"KPTI","title":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000108514621001037/0001085146-21-001037-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"CONSONANCE CAPITAL MANAGEMENT LP","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000108514621001037/kptia2_21621.htm","primary":true,"translateUrl":null,"linkName":"kptia2_21621.htm","type":"SC 13G/A","id":"NTFILEANoYv1x1yx1CzsVS","market":"us","size":53551}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2021-02-17 00:00","pubTimestamp":1613491200,"title_zh":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11880624","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312521044994-KPTI","pdf_url":null,"pub_time":1613404800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","symbol":"KPTI","title":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521044994/0001193125-21-044994-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13G/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1364719/000119312521044994/d128602dsc13ga.htm","primary":true,"translateUrl":null,"linkName":"d128602dsc13ga.htm","type":"SC 13G/A","id":"NTFILE6rsioq8Twho7GQ43","market":"us","size":65659}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2021-02-16 00:00","pubTimestamp":1613404800,"title_zh":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11867063","market":"us","labels":[],"media":"sec.gov","original_id":"AN130692321000018-KPTI","pdf_url":null,"pub_time":1613404800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","symbol":"KPTI","title":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000130692321000018/0001306923-21-000018-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1306923/000130692321000018/Karyopharm_13G_A5.pdf","primary":true,"translateUrl":null,"linkName":"Karyopharm_13G_A5.pdf","type":"SC 13G/A","id":"NTFILEDa2iYi1jZoYw8UGr","market":"us","size":194275}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2021-02-16 00:00","pubTimestamp":1613404800,"title_zh":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11866301","market":"us","labels":[],"media":"sec.gov","original_id":"AN121390021009573-KPTI","pdf_url":null,"pub_time":1613404800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","symbol":"KPTI","title":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000121390021009573/0001213900-21-009573-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"AMENDMENT NO. 6 TO SCHEDULE 13G","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000121390021009573/ea135342-13ga6chione_karyo.htm","primary":true,"translateUrl":null,"linkName":"ea135342-13ga6chione_karyo.htm","type":"SC 13G/A","id":"NTFILEEPU6XfTzjMjX3qYE","market":"us","size":207010},{"description":"POWER OF ATTORNEY, DATED AS OF FEBRUARY 12, 2021, MADE BY MARCIN CZERNIK AND CHI","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000121390021009573/ea135342ex24-1_karyo.htm","primary":false,"translateUrl":null,"linkName":"ea135342ex24-1_karyo.htm","type":"EX-24.1","id":"NTFILE8suscGKoDrncphVU","market":"us","size":8377},{"description":"POWER OF ATTORNEY, DATED AS OF FEBRUARY 12, 2021, MADE BY ANDREAS HADJIMICHAEL A","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000121390021009573/ea135342ex24-2_karyo.htm","primary":false,"translateUrl":null,"linkName":"ea135342ex24-2_karyo.htm","type":"EX-24.2","id":"NTFILE3S8XeAXaS7XWy3WV","market":"us","size":7833},{"description":"POWER OF ATTORNEY, DATED FEBRUARY 12, 2021, MADE BY GEORGE HADJIMICHAEL AND CHIO","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000121390021009573/ea135342ex24-3_karyo.htm","primary":false,"translateUrl":null,"linkName":"ea135342ex24-3_karyo.htm","type":"EX-24.3","id":"NTFILE3wt3XciTvQBRyN6w","market":"us","size":8111},{"description":"POWER OF ATTORNEY, DATED FEBRUARY 12, 2021, MADE BY WIACZESLAW SMOLOKOWSKI IN FA","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000121390021009573/ea135342ex24-4_karyo.htm","primary":false,"translateUrl":null,"linkName":"ea135342ex24-4_karyo.htm","type":"EX-24.4","id":"NTFILE9d3CUVuwtPiT74Ms","market":"us","size":7566},{"description":"POWER OF ATTORNEY, DATED FEBRUARY 12, 2021, MADE BY ANASTASIOS NIKOLAOU AND CHIO","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000121390021009573/ea135342ex24-5_karyo.htm","primary":false,"translateUrl":null,"linkName":"ea135342ex24-5_karyo.htm","type":"EX-24.5","id":"NTFILE23HMjVp8dcXoKybc","market":"us","size":8098},{"description":"JOINT FILING AGREEMENT, DATED FEBRUARY 11, 2021, AMONG THE REPORTING PERSONS","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000121390021009573/ea135342ex99-1_karyo.htm","primary":false,"translateUrl":null,"linkName":"ea135342ex99-1_karyo.htm","type":"EX-99.1","id":"NTFILEALaHyp2zBetEsXb8","market":"us","size":5686}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2021-02-16 00:00","pubTimestamp":1613404800,"title_zh":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11866300","market":"us","labels":[],"media":"sec.gov","original_id":"AN108514621000926-KPTI","pdf_url":null,"pub_time":1613404800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","symbol":"KPTI","title":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000108514621000926/0001085146-21-000926-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"CONSONANCE CAPITAL MANAGEMENT LP","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000108514621000926/kptia2_21621.htm","primary":true,"translateUrl":null,"linkName":"kptia2_21621.htm","type":"SC 13G/A","id":"NTFILE9JMYYSypNCRwbmYS","market":"us","size":53640}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2021-02-16 00:00","pubTimestamp":1613404800,"title_zh":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11831242","market":"us","labels":[],"media":"sec.gov","original_id":"AN90266421001247-KPTI","pdf_url":null,"pub_time":1613059200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","symbol":"KPTI","title":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000090266421001247/0000902664-21-001247-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"KARYOPHARM THERAPEUTICS INC.","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000090266421001247/p21-0335sc13ga.htm","primary":true,"translateUrl":null,"linkName":"p21-0335sc13ga.htm","type":"SC 13G/A","id":"NTFILE2AoqX5uqqSZtGc5s","market":"us","size":54551}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2021-02-12 00:00","pubTimestamp":1613059200,"title_zh":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":false,"id":"11817175","market":"us","labels":[],"media":"sec.gov","original_id":"AN9375121000312-KPTI","pdf_url":null,"pub_time":1612972800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","symbol":"KPTI","title":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000009375121000312/0000093751-21-000312-index.htm","us_notice_code":"Form SC 13G","us_title_en":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2021-02-11 00:00","pubTimestamp":1612972800,"title_zh":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11813989","market":"us","labels":[],"media":"sec.gov","original_id":"AN90266421001151-KPTI","pdf_url":null,"pub_time":1612972800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","symbol":"KPTI","title":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000090266421001151/0000902664-21-001151-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"KARYOPHARM THERAPEUTICS INC.","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1165408/000090266421001151/p21-0451sc13ga.htm","primary":true,"translateUrl":null,"linkName":"p21-0451sc13ga.htm","type":"SC 13G/A","id":"NTFILE3J6YpVABuXDnghan","market":"us","size":105739}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2021-02-11 00:00","pubTimestamp":1612972800,"title_zh":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11813433","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312521037306-KPTI","pdf_url":null,"pub_time":1612972800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"KPTI","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521037306/0001193125-21-037306-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521037306/d132165dex991.htm","primary":true,"translateUrl":null,"linkName":"d132165dex991.htm","type":"EX-99.1","id":"NTFILE8WH3VPQSwFTuckBt","market":"us","size":113425},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521037306/d132165d8k.htm","primary":false,"translateUrl":null,"linkName":"d132165d8k.htm","type":"8-K","id":"NTFILE6wAz6GKbMWPwwpzM","market":"us","size":24449},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521037306/g132165g0211012609529.jpg","primary":false,"translateUrl":null,"linkName":"g132165g0211012609529.jpg","type":"GRAPHIC","id":"NTFILE293HfAjJQ67jDiqv","market":"us","size":3606}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2021-02-11 00:00","pubTimestamp":1612972800,"title_zh":"8-K  - Current report","summary_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":false,"id":"11813431","market":"us","labels":[],"media":"sec.gov","original_id":"AN83423721002036-KPTI","pdf_url":null,"pub_time":1611676800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","symbol":"KPTI","title":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000083423721002036/0000834237-21-002036-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2021-01-27 00:00","pubTimestamp":1611676800,"title_zh":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11429115","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312521005821-KPTI","pdf_url":null,"pub_time":1610294400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"KPTI","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521005821/0001193125-21-005821-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521005821/d883198dex991.htm","primary":true,"translateUrl":null,"linkName":"d883198dex991.htm","type":"EX-99.1","id":"NTFILEEbPz6AA8CCug3MZt","market":"us","size":41663},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521005821/d883198d8k.htm","primary":false,"translateUrl":null,"linkName":"d883198d8k.htm","type":"8-K","id":"NTFILE4HxaPc7M15wKYtve","market":"us","size":25778},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312521005821/g883198g0109070936206.jpg","primary":false,"translateUrl":null,"linkName":"g883198g0109070936206.jpg","type":"GRAPHIC","id":"NTFILEAZvCk2FKLAFMdm8G","market":"us","size":3606}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2021-01-11 00:00","pubTimestamp":1610294400,"title_zh":"8-K  - Current report","summary_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11207429","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312520321067-KPTI","pdf_url":null,"pub_time":1608220800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"KPTI","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000119312520321067/0001193125-20-321067-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312520321067/d45154dex991.htm","primary":true,"translateUrl":null,"linkName":"d45154dex991.htm","type":"EX-99.1","id":"NTFILE9unz4R6gxZSh723M","market":"us","size":43234},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312520321067/d45154d8k.htm","primary":false,"translateUrl":null,"linkName":"d45154d8k.htm","type":"8-K","id":"NTFILEDj3TRAFcWZFbGoXx","market":"us","size":25776},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312520321067/g45154karyopharm.jpg","primary":false,"translateUrl":null,"linkName":"g45154karyopharm.jpg","type":"GRAPHIC","id":"NTFILE68L62MG66uY4g8Zu","market":"us","size":10073}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2020-12-18 00:00","pubTimestamp":1608220800,"title_zh":"8-K  - Current report","summary_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"11207431","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312520320040-KPTI","pdf_url":null,"pub_time":1608134400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"KPTI","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1503802/000119312520320040/0001193125-20-320040-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 5.03: Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-3.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312520320040/d26357dex31.htm","primary":true,"translateUrl":null,"linkName":"d26357dex31.htm","type":"EX-3.1","id":"NTFILEA15TyA5v1SyLmUhg","market":"us","size":137639},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1503802/000119312520320040/d26357d8k.htm","primary":false,"translateUrl":null,"linkName":"d26357d8k.htm","type":"8-K","id":"NTFILE2HNbRkBDyBNL2HUD","market":"us","size":37092}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2020-12-17 00:00","pubTimestamp":1608134400,"title_zh":"8-K  - Current report","summary_en":"Item 5.03: Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0}],"pageSize":20,"totalPage":12,"pageCount":8,"totalSize":236,"code":"91000000","status":"200"}]}}