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Orchestra BioMed

6.12

+0.31005.34%

Post-market: 6.11-0.0099-0.16%16:54 EDT

Volume:464.42K

Turnover:2.80M

Market Cap:366.47M

PE:-6.12

High:6.25

Open:5.87

Low:5.76

Close:5.81

52wk High:6.25

52wk Low:2.20

Shares:59.88M

Float Shares:33.00M

Volume Ratio:1.09

T/O Rate:1.41%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.9995

EPS(LYR):-1.1091

ROE:-397.30%

ROA:-45.73%

PB:18.97

PE(LYR):-5.52

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Overview Company News Filings

Analysts Offer Insights on Healthcare Companies: Enanta Pharmaceuticals (ENTA) and Orchestra BioMed Holdings (OBIO)

Orchestra BioMed gives clinical, regulatory update on BACKBEAT trial timeline

Orchestra BioMed targets BACKBEAT trial enrollment completion by end-Q3 2026

U.S. Earnings Preview: After Market Close May 8

Orchestra BioMed receives $15M payment from Ligand

Press Release: Orchestra BioMed Receives $15 Million Investment from Ligand Under Previously Announced Strategic Financing Agreement

Orchestra Biomed Receives $20 Million Payment From Medtronic Under Previously Announced Financing Agreement

THOMSON REUTERS

Orchestra Biomed Holdings Inc expected to post a loss of 43 cents a share - Earnings Preview

Orchestra granted additional breakthrough device designation for AVIM therapy

Orchestra BioMed wins FDA Breakthrough Device designation for AVIM hypertension therapy

FDA Grants Orchestra Biomed Additional Breakthrough Device Designation for Avim Therapy

THOMSON REUTERS

RTW Investments reports disposal of 32 Orchestra BioMed shares for $132.16

Orchestra BioMed says MODERATO II trial shows 13.2 mmHg AVIM blood pressure drop

Orchestra BioMed presentation highlights pivotal trials for hypertension pacing, sirolimus artery therapy

Orchestra BioMed publishes corporate deck highlighting pivotal AVIM hypertension, Virtue SAB artery disease trials

Orchestra BioMed Publishes CRT 2026 AVIM Therapy Presentation

Analysts’ Top Healthcare Picks: Orchestra BioMed Holdings (OBIO), Cardinal Health (CAH)

Orchestra BioMed CEO and Chairperson David P. Hochman acquires USD 42,900 in common shares

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This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Orchestra Biomed Holdings Inc","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260512:nNDL6F7ffD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1116320737.USD","IE00BGHQF631.EUR","BK4566","LU0265550359.USD","LU0320765489.SGD","LU1571399168.USD","LU1244550221.USD","LU2023251221.USD","BK4533","LU2089984988.USD","LU2112291526.USD","LU0208291251.USD","LU1506573853.SGD","LU0070302665.USD","LU0265550946.USD","LU1023059063.AUD","IE00BQXX3D17.EUR","OBIO","LU1989771016.USD","LU1116320901.HKD","LU1291159041.SGD","IE00BFXG1179.USD","IE00BVYPNW00.USD","LU0162691827.USD","LU0211326839.USD","LU0314106906.USD","LU1989764748.USD","LU1061106388.HKD","LU1057294990.SGD","LU0006306889.USD","LU1983299246.USD","IE00B3PB1722.GBP","IE00BQXX3C00.GBP","IE00BDGV0183.EUR","MDT","LU0211331839.USD","BK4588","LU0976567544.SGD","LU0122379950.USD","LU0211326755.USD","BK4082","LU2111349929.HKD","IE00BQXX3F31.USD","LU1244550494.USD","BK4585","IE00B3T34201.USD","LU2089283258.USD","IE00B42XCP33.USD","LU2028103732.USD","LU1244550577.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634461186","title":"U.S. Earnings Preview: After Market Close May 8","url":"https://stock-news.laohu8.com/highlight/detail?id=2634461186","media":"Dow Jones","labels":["preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634461186?lang=en_us&edition=fundamental","pubTime":"2026-05-09 03:31","pubTimestamp":1778268660,"startTime":"0","endTime":"0","summary":"This article was automatically generated by Dow Jones using technology from Automated Insights.The following companies are among those expected to report their latest financial results after the market closes.Janus Henderson Group PLC's first-quarter EPS is forecast at 99 cents, compared with 77 cents in the prior-year period. Adjusted EPS is forecast at 96 cents.Radnet Inc.'s first-quarter EPS is forecast at a loss of 25 cents, compared with a loss of 51 cents in the prior-year period. Adjusted EPS is forecast at a loss of 16 cents.Hawaiian Electric Industries Inc.'s first-quarter EPS is forecast at 38 cents, compared with 15 cents in the prior-year period. Adjusted EPS is forecast at 27 cents.AnaptysBio Inc.'s first-quarter EPS is forecast at a loss of 74 cents, compared with a loss of $1.28 in the prior-year period. Adjusted EPS is forecast at a loss of 64 cents.Biomea Fusion Inc.'s first-quarter EPS is forecast at a loss of 28 cents, compared with a loss of 80 cents in the prior-ye","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B3QW5Z07.USD","RDNT","IE00BGHQF748.EUR","LU2065731478.USD","HE","OBIO","IE00B64PRP62.GBP","BK4196","BK4139","BK4539","LU0054578231.USD","BK4135","BK4585","ANAB","JHG","BK4082","BK4081","BMEA"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633969821","title":"Orchestra BioMed receives $15M payment from Ligand","url":"https://stock-news.laohu8.com/highlight/detail?id=2633969821","media":"TIPRANKS","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633969821?lang=en_us&edition=fundamental","pubTime":"2026-05-07 13:00","pubTimestamp":1778130015,"startTime":"0","endTime":"0","summary":"Orchestra BioMed (OBIO) announced the receipt of a $15M payment from Ligand (LGND) pursuant to the previously disclosed revenue participation right...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/orchestra-biomed-receives-15m-payment-from-ligand-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/orchestra-biomed-receives-15m-payment-from-ligand-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","OBIO","BK4007","LU0566484027.USD","LGND","LU1559883803.SGD","IE0009354923.USD","BK4082"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633513859","title":"Press Release: Orchestra BioMed Receives $15 Million Investment from Ligand Under Previously Announced Strategic Financing Agreement","url":"https://stock-news.laohu8.com/highlight/detail?id=2633513859","media":"Dow Jones","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633513859?lang=en_us&edition=fundamental","pubTime":"2026-05-06 20:01","pubTimestamp":1778068860,"startTime":"0","endTime":"0","summary":"-- $15 million payment fulfills previously scheduled tranche under. royalty-based financing agreement, bringing total capital received from. Ligand to $40 million to date in exchange for tiered royalty interest in. Orchestra BioMed's future revenue as well as equity. -- Funding supports continued execution of Orchestra BioMed's pivotal trials. -- This payment, together with a $20 million investment from Medtronic. fresh strategic capital received on May 1, 2026 under previously. \"We and Ligand designed our strategic capital partnership to align funding with execution, and the receipt of this additional tranche from Ligand reflects continued and timely progress against that plan,\" said David Hochman, Chairman and Chief Executive Officer of Orchestra BioMed. \"We congratulate Ligand on an outstanding run of recent successes in its portfolio and its continued strategic growth. We believe Orchestra BioMed's programs can contribute meaningfully to Ligand's continued royalty growth in the nex","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00BVYPNV92.GBP","LU0208291251.USD","BK4566","LU1989764664.SGD","R","IE00BGHQF631.EUR","LU0122379950.USD","LU2089984988.USD","BK4585","BK4604","BK4232","LU1989771016.USD","LU1983299246.USD","LU0976567544.SGD","LU1057294990.SGD","LU2111349929.HKD","LU1061106388.HKD","LU0265550359.USD","LU2028103732.USD","LU0162691827.USD","TM","LU0211326755.USD","LU1116320737.USD","03160","LU0211331839.USD","IE00B3PB1722.GBP","LU0320765489.SGD","IE00BQXX3F31.USD","LU0211326839.USD","LU0265550946.USD","BK4099","LU2271345857.HKD","OBIO","LU1244550494.USD","LU0072461881.USD","LU0006306889.USD","LU1244550577.SGD","LU2468319806.SGD","BK4588","BK4022","IE00BQXX3C00.GBP","IE00BQXX3D17.EUR","LU0106261372.USD","LU1291159041.SGD","MDT","IE00BFXG1179.USD","LU2023251221.USD","IE00B3T34201.USD","LU0314106906.USD","IE000M9KFDE8.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633388651","title":"Orchestra Biomed Receives $20 Million Payment From Medtronic Under Previously Announced Financing Agreement","url":"https://stock-news.laohu8.com/highlight/detail?id=2633388651","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633388651?lang=en_us&edition=fundamental","pubTime":"2026-05-06 20:00","pubTimestamp":1778068804,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260506:nTUA5GNP83:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IE00B42XCP33.USD","LU0211326755.USD","LU0265550946.USD","LU1244550494.USD","BK4566","LU1057294990.SGD","LU1116320901.HKD","LU1244550577.SGD","LU0211326839.USD","LU1506573853.SGD","IE00BDGV0183.EUR","LU1989764664.SGD","LU2468319806.SGD","LU2112291526.USD","LU2089283258.USD","LU0158827781.USD","LU0072461881.USD","LU0122379950.USD","IE00BGHQF631.EUR","LU2023251221.USD","IE00BQXX3D17.EUR","LU0314106906.USD","IE00BQXX3C00.GBP","LU1571399168.USD","BK4533","LU2089284900.SGD","IE00BQXX3F31.USD","LU0106261372.USD","IE00BFXG1179.USD","LU2271345857.HKD","LU2028103732.USD","LU1989771016.USD","MDT","LU1983299246.USD","LU1291159041.SGD","LU0162691827.USD","IE00BVYPNW00.USD","LU0265550359.USD","LU2111349929.HKD","IE00B3PB1722.GBP","LU0158827948.USD","LU0006306889.USD","IE00B3T34201.USD","LU0070302665.USD","LU0211331839.USD","LU0320765489.SGD","BK4082","IE00BVYPNV92.GBP","LU0976567544.SGD","OBIO"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632647593","title":"Orchestra Biomed Holdings Inc  expected to post a loss of 43 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2632647593","media":"Reuters","labels":["preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632647593?lang=en_us&edition=fundamental","pubTime":"2026-05-02 04:16","pubTimestamp":1777666566,"startTime":"0","endTime":"0","summary":"Orchestra Biomed Holdings Inc  expected to post a loss of43cents a share - Earnings Preview Orchestra Biomed Holdings Inc OBIO.OQ OBIO.O is expected to  show a fall in quarterly revenue when it report","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260501:nL8N41E1WQ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["OBIO","NHC.AU","BK7083","BK4082"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632244668","title":"Orchestra granted additional breakthrough device designation for AVIM therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2632244668","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632244668?lang=en_us&edition=fundamental","pubTime":"2026-05-01 03:15","pubTimestamp":1777576518,"startTime":"0","endTime":"0","summary":"Orchestra BioMed (OBIO) announced that the FDA has granted a second breakthrough device designation, or BDD, for AVIM therapy specific to patients ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/orchestra-granted-additional-breakthrough-device-designation-for-avim-therapy-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/orchestra-granted-additional-breakthrough-device-designation-for-avim-therapy-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LABU","OBIO","BK4585","BK4082","BK4588"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631640630","title":"Orchestra BioMed wins FDA Breakthrough Device designation for AVIM hypertension therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2631640630","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631640630?lang=en_us&edition=fundamental","pubTime":"2026-04-30 21:01","pubTimestamp":1777554082,"startTime":"0","endTime":"0","summary":"FDA granted Orchestra BioMed second Breakthrough Device Designation for AVIM Therapy in pacemaker-indicated patients with uncontrolled hypertension despite medication.Combined designations cover more than 7.7 million US adults with hypertension despite medication.Decision supports accelerated review path for AVIM Therapy, which is being evaluated in BACKBEAT global pivotal trial run with Medtronic.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260430:nNDLbZ8QHR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2111349929.HKD","IE00BDGV0183.EUR","NDAQ","LU0162691827.USD","LU2112291526.USD","IE00BN0W2V16.EUR","MDT","LU0314104364.USD","IE00BFXG1179.USD","OBIO","LU1506573853.SGD","LU0070302665.USD","IE00BQXX3D17.EUR","SG9999014005.SGD","LU1244550221.USD","IE00BGHQF631.EUR","LU2089283258.USD","LU1571399168.USD","LU1057294990.SGD","IE000M9KFDE8.USD","LU0211326839.USD","IE00BN0W2T93.GBP","LU0211331839.USD","LU1983299246.USD","LU1291159041.SGD","LU2271345857.HKD","LU0496365809.HKD","LU0976567544.SGD","LU1023059063.AUD","BK4533","LU0211326755.USD","LU0158827781.USD","SG9999014039.USD","BK4588","LU1116320737.USD","BK4566","LU1989764748.USD","IE00B64PRP62.GBP","LU0122379950.USD","LU0072461881.USD","LU2028103732.USD","LU0432979614.USD","LU1244550577.SGD","SG9999014021.USD","LU1061106388.HKD","LU0158827948.USD","LU0006306889.USD","BK4585","LU0265550946.USD","LU1989771016.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631630504","title":"FDA Grants Orchestra Biomed Additional Breakthrough Device Designation for Avim Therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2631630504","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631630504?lang=en_us&edition=fundamental","pubTime":"2026-04-30 21:00","pubTimestamp":1777554004,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260430:nTUA4MHPQT:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4566","LU1989764748.USD","LU2112291526.USD","LU2468319806.SGD","LU0320765489.SGD","LU1057294990.SGD","LU1983299246.USD","LU1244550221.USD","LU2028103732.USD","BK4082","LU0162691827.USD","IE00BGHQF631.EUR","LU0158827948.USD","IE00BQXX3C00.GBP","MDT","LU1506573853.SGD","LU0976567544.SGD","LU1989764664.SGD","LU2271345857.HKD","OBIO","IE00BFXG1179.USD","IE000M9KFDE8.USD","LU0072461881.USD","LU1989771016.USD","IE00BVYPNW00.USD","LU1116320737.USD","LU2089283258.USD","LU0070302665.USD","LU0122379950.USD","LU1244550577.SGD","LU0106261372.USD","IE00B3PB1722.GBP","LU2089284900.SGD","LU0265550946.USD","IE00BVYPNV92.GBP","BK4533","LU2023251221.USD","IE00BQXX3F31.USD","LU2089984988.USD","LU2111349929.HKD","IE00BDGV0183.EUR","IE00B3T34201.USD","LU0158827781.USD","LU1571399168.USD","LU1023059063.AUD","LU0006306889.USD","LU0211326755.USD","LU0496365809.HKD","LU1244550494.USD","LU1291159041.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631227505","title":"RTW Investments reports disposal of 32 Orchestra BioMed shares for $132.16","url":"https://stock-news.laohu8.com/highlight/detail?id=2631227505","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631227505?lang=en_us&edition=fundamental","pubTime":"2026-04-30 05:47","pubTimestamp":1777499242,"startTime":"0","endTime":"0","summary":"RTW Investments reported exercise of pre-funded warrants into 1,250,032 Orchestra BioMed common shares on April 27, 2026.Issuer withheld 32 shares to cover exercise price, leaving 1,250,000 shares issued to RTW funds.RTW funds reported 9,556,063 Orchestra BioMed common shares beneficially owned following transactions.Pre-funded warrants were reported at an exercise price of $0.0001 per share.RTW funds reported 2,386,331 pre-funded warrants beneficially owned following transaction.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Orchestra Biomed Holdings Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260429:nNDL15nlRn:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"RTW Investments reports disposal of 32 Orchestra BioMed shares for $132.16","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["OBIO","BK4082"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629562188","title":"Orchestra BioMed says MODERATO II trial shows 13.2 mmHg AVIM blood pressure drop","url":"https://stock-news.laohu8.com/highlight/detail?id=2629562188","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629562188?lang=en_us&edition=fundamental","pubTime":"2026-04-24 00:01","pubTimestamp":1776960085,"startTime":"0","endTime":"0","summary":"Orchestra BioMed flagged new clinical and mechanistic data for its Atrioventricular Interval Modulation  Therapy, slated for presentation at Heart Rhythm Society  2026.Pre-randomization set-up results from MODERATO II showed blood pressure fell immediately for most patients following therapy activation.Six-month follow-up indicated many patients maintained blood pressure control, supporting potential durability of effect in an older, higher-risk population.Separate pressure-volume loop findings, already published in JACC: Clinical Electrophysiology, showed AVIM lowered systolic blood pressure versus standard pacing while preserving overall heart pumping strength.Orchestra BioMed highlighted BACKBEAT Global Pivotal Trial enrollment with Medtronic, positioning upcoming readouts as key validation for broader commercialization.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260423:nNDLb8Rc7x:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1571399168.USD","LU1244550577.SGD","IE00B3PB1722.GBP","SG9999014005.SGD","BK4585","LU0072461881.USD","LU0211326839.USD","OBIO","LU2210149790.SGD","IE00BGHQF748.EUR","BK4533","NDAQ","BK4112","IE00BVYPNV92.GBP","LU0320765489.SGD","LU0976567544.SGD","LU2271345857.HKD","IE000M9KFDE8.USD","IE00BQXX3D17.EUR","IE00BQXX3F31.USD","LU1989771016.USD","IE00BFXG1179.USD","LU0314104364.USD","LU0106261372.USD","BK4082","LU0432979614.USD","LU2210150020.SGD","IE00B42XCP33.USD","LU2112291526.USD","IE00BN0W2T93.GBP","LU1116320901.HKD","LU1061106388.HKD","LU1023059063.AUD","LU0496365809.HKD","SG9999014021.USD","LU0158827781.USD","LU2111349929.HKD","MDT","IE00B3T34201.USD","LU2089284900.SGD","IE00BQXX3C00.GBP","BK4588","LU0006306889.USD","LU2089984988.USD","IE00B3QW5Z07.USD","LU0122379950.USD","LU1116320737.USD","LU2095319765.USD","LU0265550359.USD","IE00BVYPNW00.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625677137","title":"Orchestra BioMed presentation highlights pivotal trials for hypertension pacing, sirolimus artery therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2625677137","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625677137?lang=en_us&edition=fundamental","pubTime":"2026-04-06 22:59","pubTimestamp":1775487592,"startTime":"0","endTime":"0","summary":"Orchestra BioMed outlined two pivotal-stage cardiovascular programs, AVIM Therapy for uncontrolled hypertension in pacemaker-indicated patients and Virtue SAB for atherosclerotic artery disease.AVIM Therapy BACKBEAT global pivotal trial is actively enrolling up to 500 patients across about 130 sites, with primary efficacy endpoint based on change in mean 24-hour ambulatory systolic blood pressure at 3 months.Virtue SAB U.S. pivotal Virtue Trial is actively enrolling 740 coronary in-stent restenosis patients in a 1:1 randomized study versus Boston Scientific AGENT paclitaxel-coated balloon, with primary endpoint target lesion failure at 12 months.Orchestra BioMed cited cash runway into Q4 2027, with $35 million in committed tranche payments from Medtronic and Ligand and up to $21 million expected from Haemonetics acquisition of Vivasure Medical.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260406:nNDL43xDhr:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0345769128.USD","LU0187121727.USD","LU0823417737.USD","LU1061106388.HKD","LU2491049909.HKD","IE00BJT1NW94.SGD","LU0012050646.USD","LU1720051017.SGD","LU2242649171.HKD","IE00BVYPNV92.GBP","LU0353189680.USD","LU0122379950.USD","LU0158827781.USD","LU0432979614.USD","LU2112291526.USD","BK4504","LU2506952097.USD","BSX","LU0314106906.USD","MDT","BK4581","LU0106261612.USD","LU1791710400.SGD","LU1989772840.SGD","IE00BQXX3F31.USD","LU0211326839.USD","HAE","BK4588","LU0158827948.USD","IE00B3T34201.USD","IE00B42XCP33.USD","IE00B64QTZ34.USD","LU0882574055.USD","LU2089284900.SGD","LU2271345857.HKD","LU2506951875.HKD","LU0823416689.USD","LU0976567544.SGD","LU1169589451.USD","LU2244417387.USD","LU1244550494.USD","LU1718418525.SGD","IE00B4R5TH58.HKD","LU0238689110.USD","LU0528227936.USD","LU1244550221.USD","IE00B19Z6F94.USD","OBIO","BK4533","LU1804176565.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2623342692","title":"Orchestra BioMed publishes corporate deck highlighting pivotal AVIM hypertension, Virtue SAB artery disease trials","url":"https://stock-news.laohu8.com/highlight/detail?id=2623342692","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2623342692?lang=en_us&edition=fundamental","pubTime":"2026-03-30 23:54","pubTimestamp":1774886068,"startTime":"0","endTime":"0","summary":"Orchestra BioMed highlighted two pivotal-stage programs, AVIM Therapy for cardiac pacing-based hypertension treatment, Virtue SAB for extended-release sirolimus delivery during angioplasty.BACKBEAT global pivotal trial for AVIM Therapy is actively enrolling up to 500 patients across 130 sites, with primary efficacy endpoint change in mean 24-hour ambulatory systolic blood pressure at 3 months.Virtue Trial for Virtue SAB is actively enrolling 740 patients in a U.S. pivotal coronary in-stent restenosis study, randomized 1:1 versus Boston Scientific AGENT paclitaxel-coated balloon with 12-month target lesion failure primary endpoint.Orchestra BioMed flagged expected catalysts in 2026-2027, including completion of enrollment for BACKBEAT study, primary efficacy and safety data readout, completion of Virtue Trial enrollment.Corporate update cited cash runway into Q4 2027, with committed tranche payments of USD 35 million from Medtronic and Ligand.Disclaimer: This news brief was created by P","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260330:nNDL2JnZFv:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0011850046.USD","LU0950375773.USD","IE00BVYPNW00.USD","BK4504","LU1548497426.USD","LU1791710400.SGD","BK4533","IE00B2B36J28.USD","LU0823416689.USD","LU2362540622.SGD","LU1720051017.SGD","SG9999001176.USD","IE00B42XCP33.USD","LU0251132253.USD","LU2357305700.SGD","LU0211326755.USD","LU2089984988.USD","BSX","LU0225283273.USD","SG9999013999.USD","IE00BQXX3D17.EUR","LU0823417737.USD","IE00BGHQF631.EUR","LU0353189680.USD","SGXZ57979304.SGD","LU0265550359.USD","LU0158827948.USD","IE00BQXX3C00.GBP","LU1983299246.USD","LU2491050154.USD","LU0528227936.USD","LU0208291251.USD","LU2506952097.USD","LU2362541273.HKD","LU0122379950.USD","LU0823417653.USD","LU1244550577.SGD","IE0002141913.USD","LU2023251221.USD","BK4082","IE00BJT1NW94.SGD","MDT","OBIO","LU0265550946.USD","LU2362541513.USD","LU0211331839.USD","LU2089283258.USD","IE00BJJMRZ35.SGD","LU2111349929.HKD","LU1057294990.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2622994970","title":"Orchestra BioMed Publishes CRT 2026 AVIM Therapy Presentation","url":"https://stock-news.laohu8.com/highlight/detail?id=2622994970","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2622994970?lang=en_us&edition=fundamental","pubTime":"2026-03-24 23:59","pubTimestamp":1774367980,"startTime":"0","endTime":"0","summary":"Orchestra BioMed published a medical research presentation on AVIM therapy, a pacemaker-based approach being studied for hypertension.The document describes AVIM therapy as delivered via Medtronic Astra or Azure dual-chamber pacemakers, with modulation of atrioventricular intervals intended to affect blood pressure.It reports results from the MODERATO II randomized, double-blind pilot study, including a 0% MACE rate at 6 months and a reduction in mean 24-hour aSBP of 14.1 mmHg at 6 months for the AVIM therapy group.The presentation also outlines the BACKBEAT Global Pivotal Trial, which is enrolling up to 500 patients across 130 sites and uses change in mean 24-hour aSBP at 3 months as the primary efficacy endpoint.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, in","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260324:nNDL5rgwdD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0070302665.USD","LU0211331839.USD","IE00B3T34201.USD","LU2111349929.HKD","LU2271345857.HKD","LU1061106388.HKD","LU0122379950.USD","OBIO","LU0211326755.USD","LU0208291251.USD","LU1506573853.SGD","LU0496365809.HKD","IE00BDGV0183.EUR","LU0320765489.SGD","IE00BGHQF631.EUR","IE00BQXX3C00.GBP","LU0432979614.USD","LU1989771016.USD","MDT","LU0158827781.USD","IE00B3PB1722.GBP","LU1116320737.USD","LU1989764748.USD","LU2089283258.USD","BK4082","LU0211326839.USD","IE00BVYPNV92.GBP","BK4566","IE00B42XCP33.USD","LU1023059063.AUD","LU2089284900.SGD","LU0265550359.USD","IE00BVYPNW00.USD","LU2468319806.SGD","LU2028103732.USD","LU1116320901.HKD","LU2089984988.USD","LU0314106906.USD","LU2023251221.USD","IE000M9KFDE8.USD","LU1571399168.USD","IE00BQXX3D17.EUR","LU1057294990.SGD","LU0158827948.USD","LU1244550577.SGD","LU0162691827.USD","BK4585","LU0072461881.USD","BK4533","LU0976567544.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620238026","title":"Analysts’ Top Healthcare Picks: Orchestra BioMed Holdings (OBIO), Cardinal Health (CAH)","url":"https://stock-news.laohu8.com/highlight/detail?id=2620238026","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620238026?lang=en_us&edition=fundamental","pubTime":"2026-03-18 15:40","pubTimestamp":1773819622,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 3 analysts just weighed in on Orchestra BioMed Holdings (OBIO – Research Report), ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-top-healthcare-picks-orchestra-biomed-holdings-obio-cardinal-health-cah-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-top-healthcare-picks-orchestra-biomed-holdings-obio-cardinal-health-cah-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0128525689.USD","XBI","LU0162691827.USD","HCSG","LU1267930227.SGD","XLV","LU1880398471.USD","LU1267930813.SGD","LU0310800965.SGD","LU0029874061.USD","LU1267930490.SGD","LU0154236417.USD","BK4585","LU0072461881.USD","BK4137","LU1880398554.USD","LU0889566641.SGD","CAH","LU0310799852.SGD","BK4082","LU0128526141.USD","BK4588","LU0052756011.USD","LU0006061336.USD","OBIO","LU0211328371.USD","LU1571399168.USD","SG9999001440.SGD","BK4581","LABU","LU0792757196.USD","BK4175","LU0211327993.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620449457","title":"Orchestra BioMed CEO and Chairperson David P. Hochman acquires USD 42,900 in common shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2620449457","media":"Reuters","labels":["insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620449457?lang=en_us&edition=fundamental","pubTime":"2026-03-17 04:55","pubTimestamp":1773694513,"startTime":"0","endTime":"0","summary":"David Hochman, Chief Executive Officer and Chairperson of Orchestra BioMed, reported buying 10,000 common shares. The weighted average purchase price was USD 4.29 per share. Following the acquisition, he reported direct ownership of 1,086,467 common shares.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Orchestra Biomed Holdings Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on March 16, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260316:nNDL2KwzBl:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":"Orchestra BioMed CEO and Chairperson David P. Hochman acquires USD 42,900 in common shares","news_tag":"insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4082","OBIO"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":4,"pageCount":4,"totalSize":78,"code":"91000000","status":"200"}]}}