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Rhythm Pharmaceuticals Inc.

104.41

+2.212.16%

Volume:186.06K

Turnover:19.37M

Market Cap:7.19B

PE:-33.50

High:105.30

Open:102.96

Low:102.25

Close:102.20

52wk High:122.20

52wk Low:74.50

Shares:68.85M

Float Shares:65.39M

Volume Ratio:0.87

T/O Rate:0.28%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.1172

EPS(LYR):-3.1100

ROE:-117.04%

ROA:-30.96%

PB:69.81

PE(LYR):-33.57

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Overview Company News Filings

Rhythm Pharmaceuticals reports Phase 3 EMANATE trial misses primary endpoints for setmelanotide across four genetic substudies

Rhythm Pharmaceuticals Inc: Plans to Continue Analysis of Emanate Dataset & Evaluate Potential Clinical Development Paths Forward

THOMSON REUTERS

Rhythm Pharmaceuticals Inc - No New Safety Signals Observed With Setmelanotide in Emanate Trial

THOMSON REUTERS

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Pharmaceuticals reports Phase 3 EMANATE trial misses primary endpoints for setmelanotide across four genetic substudies","url":"https://stock-news.laohu8.com/highlight/detail?id=2620499858","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620499858?lang=en_us&edition=fundamental","pubTime":"2026-03-17 04:01","pubTimestamp":1773691291,"startTime":"0","endTime":"0","summary":"Rhythm Pharmaceuticals reports Phase 3 EMANATE trial misses primary endpoints for setmelanotide across four genetic substudies. Rhythm reported topline results from the global Phase 3 EMANATE trial of setmelanotide in four genetic substudies of MC4R-pathway obesity, and all four substudies did not meet their pre-specified primary endpoints at Week 52. In the prespecified modified ITT analysis, placebo-adjusted BMI reductions at Week 52 were 0% or greater in POMC/PCSK1 heterozygous patients  and SRC1  patients (-4%). Post hoc analyses using last observation carried forward found statistically significant BMI reductions at Week 52 in POMC/PCSK1 heterozygous patients  and SRC1  patients . The company said the safety profile was consistent with prior studies, with common adverse events including skin hyperpigmentation and injection-site reactions. The results were announced with a conference call scheduled for later the same day, and no separate future scientific presentation was specified","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260316:nNDL7fQJvC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00BGHQF748.EUR","LU0314104364.USD","LU2210149790.SGD","LU2095319765.USD","IE00B3QW5Z07.USD","IE00BKPKM429.USD","SG9999014005.SGD","NDAQ","SG9999014039.USD","BK4139","IE00BN0W2V16.EUR","BK4112","IE00BN0W2T93.GBP","LU2210150020.SGD","BK4588","RYTM","BK4585","IE00BN0W2W23.USD","SG9999014021.USD","SG9999014013.SGD","IE00B64PRP62.GBP"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620960714","title":"Rhythm Pharmaceuticals Inc: Plans to Continue Analysis of Emanate Dataset & Evaluate Potential Clinical Development Paths Forward","url":"https://stock-news.laohu8.com/highlight/detail?id=2620960714","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620960714?lang=en_us&edition=fundamental","pubTime":"2026-03-17 04:01","pubTimestamp":1773691260,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260316:nTUA1NY8SX:4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4588","BK4585","RYTM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620249600","title":"Rhythm Pharmaceuticals Inc - No New Safety Signals Observed With Setmelanotide in Emanate Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2620249600","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620249600?lang=en_us&edition=fundamental","pubTime":"2026-03-17 04:01","pubTimestamp":1773691260,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260316:nTUA1NY8SX:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BK4585","BK4588","RYTM"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":9,"pageCount":9,"totalSize":163,"code":"91000000","status":"200"}]}}