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SPYRE THERAPEUTICS INC

90.60

+1.892.13%

Post-market: 90.600.00000.00%16:59 EDT

Volume:886.05K

Turnover:79.81M

Market Cap:7.99B

PE:-45.08

High:91.41

Open:90.00

Low:87.89

Close:88.71

52wk High:110.18

52wk Low:14.51

Shares:88.17M

Float Shares:80.98M

Volume Ratio:0.88

T/O Rate:1.09%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.0100

EPS(LYR):-1.9755

ROE:-22.98%

ROA:-19.81%

PB:8.37

PE(LYR):-45.86

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Overview Company News Filings

Spyre's inflammatory bowel drug reduces disease activity in mid-stage study

Spyre Therapeutics: There Were Six Subjects With Treatment-Emergent Adverse Events During Induction Treatment Period

THOMSON REUTERS

Spyre Therapeutics: Announces Positive 12-Week Induction Data From Part a of Phase 2 Skyline Trial of Spy001

THOMSON REUTERS

Spyre Therapeutics: Spy001 Met Primary Endpoint Showing Statistically Significant Reduction in Rhi Score of 9.2 Points

THOMSON REUTERS

NASDAQ TRADE HALT HALT NEWS PENDING AT 06:55 AM

Spyre to report SKYLINE trial topline induction results for SPY001 in ulcerative colitis

Spyre Therapeutics announces annual shareholder meeting webcast

Assessing Spyre Therapeutics (SYRE) Valuation After Accelerated SKYWAY Trial Progress And Strong Share Price Momentum

Simply Wall St.

Spyre CEO Cameron Turtle disposes of $0.7 million common shares

Spyre Therapeutics CMO Sheldon Sloan disposes of common shares worth 0.4 million

Spyre CFO Scott Burrows disposes Spyre Therapeutics common stock worth $369,004.60

Spyre Therapeutics grants inducement stock options for 70,200 shares to five hires

Spyre Therapeutics Announces Grants of Inducement Awards

Analysts Offer Insights on Healthcare Companies: Bicara Therapeutics Inc. (BCAX), Spyre Therapeutics (SYRE) and Henry Schein (HSIC)

Stifel Nicolaus Remains a Buy on Spyre Therapeutics (SYRE)

Spyre Therapeutics (SYRE) Receives a Rating Update from a Top Analyst

Spyre Therapeutics Completes First-in-Human Study of SPY001-001, De-risking Early Pipeline

Spyre Therapeutics (SYRE) Valuation After Accelerated SKYWAY Trial Timeline And Rising Investor Interest

Simply Wall St.

Spyre Therapeutics (SYRE) Is Up 7.3% After Accelerating SPY072 Phase 2 POC Timeline - Has The Bull Case Changed?

Simply Wall St.

Analysts’ Top Healthcare Picks: Oneview Healthcare Chess Depository Interests repr 1 (ONVVF), Spyre Therapeutics (SYRE)

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SPY001 in ulcerative colitis","url":"https://stock-news.laohu8.com/highlight/detail?id=2626711029","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2626711029?lang=en_us&edition=fundamental","pubTime":"2026-04-11 04:09","pubTimestamp":1775851752,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics scheduled release of SPY001 Part A induction topline results from SKYLINE trial in moderate-to-severely active ulcerative colitis for April 13, 2026.Data have not been presented yet; results will be discussed on conference call and webcast at 8:00 a.m. ET on April 13, 2026.Announcement did not disclose trial outcomes, focusing instead on timing of upcoming topline readout.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief on April 10, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260410:nNDL7KmGdD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2626104891","title":"Spyre Therapeutics announces annual shareholder meeting webcast","url":"https://stock-news.laohu8.com/highlight/detail?id=2626104891","media":"Reuters","labels":["conferences","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2626104891?lang=en_us&edition=fundamental","pubTime":"2026-04-11 04:02","pubTimestamp":1775851370,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics schedules 2026 annual stockholder meeting for May 27, 2026 as virtual-only webcast.Ballot includes election of three Class I directors to terms ending at 2029 annual meeting.Stockholders will vote on advisory approval of named executive officer compensation.Meeting will also consider approval of amended and restated 2016 employee stock purchase plan.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on April 10, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260410:nNDL7MwWPs:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625964793","title":"Assessing Spyre Therapeutics (SYRE) Valuation After Accelerated SKYWAY Trial Progress And Strong Share Price Momentum","url":"https://stock-news.laohu8.com/highlight/detail?id=2625964793","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625964793?lang=en_us&edition=fundamental","pubTime":"2026-04-05 23:24","pubTimestamp":1775402667,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics (SYRE) recently accelerated its Phase 2 SKYWAY basket trial by completing enrollment for the rheumatoid arthritis sub study of SPY072 ahead of schedule, with topline data now guided for Q3 2026.\nSee our latest analysis for Spyre Therapeutics.\nThe accelerated SKYWAY timeline comes on top of a sharp run, with Spyre Therapeutics posting a 30 day share price return of 18.51% and a 90 day share price return of 58.81%. The 1 year total shareholder return of 272.01% and 3 year...","market":"us","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-syre/spyre-therapeutics/news/assessing-spyre-therapeutics-syre-valuation-after-accelerate","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-syre/spyre-therapeutics/news/assessing-spyre-therapeutics-syre-valuation-after-accelerate","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4139","LU2065732104.USD","PRGS","BK4097","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2624698202","title":"Spyre CEO Cameron Turtle disposes of $0.7 million common shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2624698202","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2624698202?lang=en_us&edition=fundamental","pubTime":"2026-04-04 09:31","pubTimestamp":1775266278,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics CEO Turtle Cameron sold 15,000 shares on April 1.Sales totaled about 0.7 million at weighted average prices of $49.2 and $49.92.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on April 03, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260404:nNDL7Znhxy:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2624698274","title":"Spyre Therapeutics CMO Sheldon Sloan disposes of common shares worth 0.4 million","url":"https://stock-news.laohu8.com/highlight/detail?id=2624698274","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2624698274?lang=en_us&edition=fundamental","pubTime":"2026-04-04 09:30","pubTimestamp":1775266244,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics Chief Medical Officer Sheldon Sloan reported sale of 7,958 shares on April 1, 2026 at USD 50.Transaction followed exercise of stock options for 7,958 shares at USD 21.66.Sloan reported 0 shares of common stock owned following transactions.Filing showed 87,542 stock options held following transaction.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on April 03, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260404:nNDL92MLgv:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Spyre Therapeutics CMO Sheldon Sloan disposes of common shares worth 0.4 million","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2624982086","title":"Spyre CFO Scott Burrows disposes Spyre Therapeutics common stock worth $369,004.60","url":"https://stock-news.laohu8.com/highlight/detail?id=2624982086","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2624982086?lang=en_us&edition=fundamental","pubTime":"2026-04-04 09:30","pubTimestamp":1775266207,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics CFO Scott L Burrows cut direct holdings to 97,994 shares in transactions dated April 1, 2026.Burrows sold 7,500 shares at USD 49.21 to USD 49.98 per share.He acquired 7,500 shares at USD 14.5 per share through an option exercise.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on April 03, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260404:nNDL162p2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2624661062","title":"Spyre Therapeutics grants inducement stock options for 70,200 shares to five hires","url":"https://stock-news.laohu8.com/highlight/detail?id=2624661062","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2624661062?lang=en_us&edition=fundamental","pubTime":"2026-04-04 04:01","pubTimestamp":1775246485,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics granted stock options covering 70,200 shares to five non-executive employees under its 2018 Equity Inducement Plan.Options carry a 10-year term with an exercise price of $48.90, based on April 1, 2026 close.Vesting starts with 25% on first anniversary of each employee’s start date.Remaining awards vest monthly at 1/48 thereafter, subject to continued service.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260403:nNDLb82G88:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","SYRE","NDAQ","LU2095319765.USD","SG9999014005.SGD","IE00BN0W2W23.USD","BK4112","BK4588","IE00BKPKM429.USD","BK4139","LU2210149790.SGD","IE00B64PRP62.GBP","SG9999014039.USD","IE00B3QW5Z07.USD","LU2210150020.SGD","SG9999014021.USD","IE00BGHQF748.EUR","SG9999014013.SGD","LU0314104364.USD","IE00BN0W2V16.EUR","IE00BN0W2T93.GBP"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2624646586","title":"Spyre Therapeutics Announces Grants of Inducement Awards","url":"https://stock-news.laohu8.com/highlight/detail?id=2624646586","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2624646586?lang=en_us&edition=fundamental","pubTime":"2026-04-04 04:01","pubTimestamp":1775246460,"startTime":"0","endTime":"0","summary":"WALTHAM, Mass., April  03, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company pioneering long-acting antibodies and ant","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/04/03/3268133/0/en/Spyre-Therapeutics-Announces-Grants-of-Inducement-Awards.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4007","LENZ","BK4539","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2623588906","title":"Analysts Offer Insights on Healthcare Companies: Bicara Therapeutics Inc. (BCAX), Spyre Therapeutics (SYRE) and Henry Schein (HSIC)","url":"https://stock-news.laohu8.com/highlight/detail?id=2623588906","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2623588906?lang=en_us&edition=fundamental","pubTime":"2026-03-31 18:40","pubTimestamp":1774953609,"startTime":"0","endTime":"0","summary":"Companies in the Healthcare sector have received a lot of coverage today as analysts weigh in on Bicara Therapeutics Inc. (BCAX), Spyre Therapeutic...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-bicara-therapeutics-inc-bcax-spyre-therapeutics-syre-and-henry-schein-hsic-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-bicara-therapeutics-inc-bcax-spyre-therapeutics-syre-and-henry-schein-hsic-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","HSIC","LABU","BK4175","SYRE","BK4137","HCSG","LU0128526141.USD","BK4585","BK4588","BK4581","BCAX","XBI","LU0029874061.USD","XLV"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2621225743","title":"Stifel Nicolaus Remains a Buy on Spyre Therapeutics (SYRE)","url":"https://stock-news.laohu8.com/highlight/detail?id=2621225743","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2621225743?lang=en_us&edition=fundamental","pubTime":"2026-03-23 01:35","pubTimestamp":1774200906,"startTime":"0","endTime":"0","summary":"Stifel Nicolaus analyst Alex Thompson CFA maintained a Buy rating on Spyre Therapeutics today and set a price target of $92.00. Thompson CFA covers...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/stifel-nicolaus-remains-a-buy-on-spyre-therapeutics-syre-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/stifel-nicolaus-remains-a-buy-on-spyre-therapeutics-syre-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SF","BK4139","BK4127","CFA","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2621821793","title":"Spyre Therapeutics (SYRE) Receives a Rating Update from a Top Analyst","url":"https://stock-news.laohu8.com/highlight/detail?id=2621821793","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2621821793?lang=en_us&edition=fundamental","pubTime":"2026-03-21 22:55","pubTimestamp":1774104945,"startTime":"0","endTime":"0","summary":"In a report released today, Sam Slutsky from LifeSci Capital maintained a Buy rating on Spyre Therapeutics, with a price target of $64.00. Slutsky ...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/spyre-therapeutics-syre-receives-a-rating-update-from-a-top-analyst-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/spyre-therapeutics-syre-receives-a-rating-update-from-a-top-analyst-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2621758706","title":"Spyre Therapeutics Completes First-in-Human Study of SPY001-001, De-risking Early Pipeline","url":"https://stock-news.laohu8.com/highlight/detail?id=2621758706","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2621758706?lang=en_us&edition=fundamental","pubTime":"2026-03-21 00:30","pubTimestamp":1774024236,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics, Inc ($SYRE) announced an update on their ongoing clinical study. Spyre Therapeutics, Inc. (SYRE) has completed a Phase 1 trial ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/spyre-therapeutics-completes-first-in-human-study-of-spy001-001-de-risking-early-pipeline?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/spyre-therapeutics-completes-first-in-human-study-of-spy001-001-de-risking-early-pipeline?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LENZ","SYRE","BK4539","BK4007","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620329007","title":"Spyre Therapeutics (SYRE) Valuation After Accelerated SKYWAY Trial Timeline And Rising Investor Interest","url":"https://stock-news.laohu8.com/highlight/detail?id=2620329007","media":"Simply Wall St.","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620329007?lang=en_us&edition=fundamental","pubTime":"2026-03-19 10:07","pubTimestamp":1773886073,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics (SYRE) is back in focus after completing recruitment for the rheumatoid arthritis arm of its SKYWAY Phase 2 trial, which has pulled forward the expected topline readout to the third quarter of 2026.\nSee our latest analysis for Spyre Therapeutics.\nAt a share price of $43.06, Spyre’s momentum has been strong, with a 30 day share price return of 17.55% and a 90 day gain of 28.65%. The 1 year total shareholder return of 134.02% and 3 year total shareholder return above 4x...","market":"hk","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-syre/spyre-therapeutics/news/spyre-therapeutics-syre-valuation-after-accelerated-skyway-t","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-syre/spyre-therapeutics/news/spyre-therapeutics-syre-valuation-after-accelerated-skyway-t","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620446649","title":"Spyre Therapeutics (SYRE) Is Up 7.3% After Accelerating SPY072 Phase 2 POC Timeline - Has The Bull Case Changed?","url":"https://stock-news.laohu8.com/highlight/detail?id=2620446649","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620446649?lang=en_us&edition=fundamental","pubTime":"2026-03-17 13:16","pubTimestamp":1773724601,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics recently reported that it has completed recruitment for the rheumatoid arthritis (RA) sub-study of its SKYWAY Phase 2 basket trial evaluating SPY072, an extended half-life TL1A-targeting antibody, and has accelerated the expected timing of topline proof-of-concept data to the third quarter of 2026 for RA and the fourth quarter of 2026 for psoriatic arthritis and axial spondyloarthritis.\nThis progress underscores how basket and platform trial designs could speed clinical...","market":"hk","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-syre/spyre-therapeutics/news/spyre-therapeutics-syre-is-up-73-after-accelerating-spy072-p","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-syre/spyre-therapeutics/news/spyre-therapeutics-syre-is-up-73-after-accelerating-spy072-p","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2620557415","title":"Analysts’ Top Healthcare Picks: Oneview Healthcare Chess Depository Interests repr 1 (ONVVF), Spyre Therapeutics (SYRE)","url":"https://stock-news.laohu8.com/highlight/detail?id=2620557415","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2620557415?lang=en_us&edition=fundamental","pubTime":"2026-03-17 08:40","pubTimestamp":1773708011,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 2 analysts just weighed in on Oneview Healthcare Chess Depository Interests repr 1...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-top-healthcare-picks-oneview-healthcare-chess-depository-interests-repr-1-onvvf-spyre-therapeutics-syre-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-top-healthcare-picks-oneview-healthcare-chess-depository-interests-repr-1-onvvf-spyre-therapeutics-syre-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4585","XLV","BK4588","XBI","SYRE","LABU","ONVVF","BK4581","BK4167","BK4139"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":10,"pageCount":9,"totalSize":184,"code":"91000000","status":"200"}]}}